85865
Stigmatellin
≥95.0% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C30H42O7
CAS Number:
Molecular Weight:
514.65
PubChem Substance ID:
UNSPSC Code:
51101500
MDL number:
Beilstein/REAXYS Number:
5319239
SMILES string
COC(\C=C\C=C\C(C)=C\C)C(C)C(OC)C(C)CCC1=C(C)C(=O)c2c(OC)cc(OC)c(O)c2O1
assay
≥95.0% (HPLC)
antibiotic activity spectrum
fungi
mode of action
enzyme | inhibits
shipped in
wet ice
storage temp.
−20°C
Biochem/physiol Actions
Antibiotic and antifungal from Stigmatella aurantiaca. Inhibits electron transport. Acts at the Qo center of the bc1 complex, binds to the heme b1 domain of cytochrome b as well as to the iron-sulfur protein. Used in studies on hydroubiquinone-cytochrome c2 oxidoreductase.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Regulatory Information
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B Kunze et al.
The Journal of antibiotics, 37(5), 454-461 (1984-05-01)
An antibiotic activity was extracted from the cell mass of the myxobacterium, Stigmatella aurantiaca strain Sg a15. The antibiotic was toxic for yeasts and filamentous fungi, but not for most bacteria. The compound had the molecular formula C30H42O7, appears to
D E Robertson et al.
Biochemistry, 32(5), 1310-1317 (1993-02-09)
The hydroubiquinone-cytochrome c2 oxidoreductase (cyt bc1) from Rhodobacter capsulatus has been solubilized according to the dodecyl maltoside method and isolated, and its minimal functional composition has been characterized. We find the complex to be composed of three protein subunits corresponding
Use of specific inhibitors on the mitochondrial bc1 complex.
G von Jagow et al.
Methods in enzymology, 126, 253-271 (1986-01-01)
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