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Merck
CN

92416

Sigma-Aldrich

D-Mannitol 1-phosphate lithium salt

≥95% (TLC)

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About This Item

Empirical Formula (Hill Notation):
C6H15O9P · xLi+
CAS Number:
Molecular Weight:
262.15 (free acid basis)
MDL number:
UNSPSC Code:
12352201
NACRES:
NA.25
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Assay

≥95% (TLC)

form

powder

color

white

storage temp.

−20°C

SMILES string

[P](=O)(OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)(O)O

InChI

1S/C6H15O9P/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14/h3-11H,1-2H2,(H2,12,13,14)/t3-,4-,5-,6-/m1/s1

InChI key

GACTWZZMVMUKNG-KVTDHHQDSA-N

Application

Mannitol-1-P can be used to detect the transphosphorylation activity of D-mannitol-specific enzyme II expreβed in spheroplasts.

Biochem/physiol Actions

D-Mannitol 1-phosphate is an intermediate in the fructose and mannose metabolism. It takes part in the phosphoenolpyruvate-dependent PEP group translocation (phosphotransferase system or PTS), a major mechanism used by bacteria for carbohydrate uptake.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Other Notes

To gain a comprehensive understanding of our extensive range of Sugar alcohols for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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L Niculescu et al.
Diabetologia, 41(8), 947-954 (1998-09-03)
When tested in the presence of an inhibitor of sorbitol dehydrogenase, both mannitol and sorbitol caused a progressive inhibition of the detritiation of [2-3H]glucose in isolated rat hepatocytes. The purpose of the present work was to investigate the possibility that
A R Neves et al.
European journal of biochemistry, 267(12), 3859-3868 (2000-06-10)
The metabolism of glucose by nongrowing cells of Lactococcus lactis strain FI7851, constructed from the wild-type L. lactis strain MG1363 by disruption of the lactate dehydrogenase (ldh) gene [Gasson, M.J., Benson, K., Swindel, S. & Griffin, H. (1996) Lait 76
H Rosenberg et al.
Journal of bacteriology, 158(1), 63-68 (1984-04-01)
The phosphate moiety of D-mannitol-1-phosphate in Escherichia coli is subject to rapid turnover and is in close equilibrium with Pi and the phosphorus of fructose-1,6-bisphosphate. These three compounds account for the bulk of 32P label found in cells after several
Stefan Krahulec et al.
Carbohydrate research, 343(9), 1414-1423 (2008-05-03)
A putative long-chain mannitol-1-phosphate 5-dehydrogenase from Aspergillus fumigatus (AfM1PDH) was overexpressed in Escherichia coli to a level of about 50% of total intracellular protein. The purified recombinant protein was a approximately 40-kDa monomer in solution and displayed the predicted enzymatic
F F Roossien et al.
Biochemistry, 23(21), 4934-4939 (1984-10-09)
Purified mannitol-specific enzyme II (EIImtl), in the presence of the detergent Lubrol, catalyzes the phosphorylation of mannitol from P-HPr via a classical ping-pong mechanism involving the participation of a phosphorylated EIImtl intermediate. This intermediate has been demonstrated by using radioactive

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