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Merck
CN

96329

Kollicoat® SR 30 D

28.5-31.5% solids basis

Synonym(s):

Poly(vinyl acetate) dispersion 30 %, Poly(vinyl acetate) stabilized with polyvinylpyrrolidone and sodium lauryl sulfate

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About This Item

CAS Number:
UNSPSC Code:
12162002
NACRES:
NA.25
MDL number:
Technical Service
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Quality Level

assay

25.0-30.0% (saponification value * 0.1534), 28.5-31.5% solids basis

form

dispersion

impurities

≤0.5% sulfated ash (verified on random samples only), ≤0.500% particulate matter, agglomerates, ≤100 ppm residual monomer vinyl acetate, ≤15000 ppm acetic acid, ≤20 ppm heavy metals (verified on random samples only), ≤4.0% povidone (N content/0.126)

pH

3.0-5.5

viscosity

≤100 mPa.s(20 °C, Brookfield RVT) (SP. 1, 100 PRM)

density

1.045-1.065

SMILES string

O(C(=O)C)C=C

InChI

1S/C4H6O2/c1-3-6-4(2)5/h3H,1H2,2H3

InChI key

XTXRWKRVRITETP-UHFFFAOYSA-N

Application

Kollicoat SR is use as a controlled-release coating or as a matrix. Kollicoat polymers can be employed as film coatings (intelligent surfaces) with controlled-release agents, for instant-release or sustained-release applications. Kollicoat polymers can be used with all standard coating equipment and are cost-effective, delivering maximum quality in terms of function, stability, and appearance. This research grade product is intended for use in R&D and development only.

Analysis Note

appearance and solubility of a film must conform

Legal Information

Kollicoat is a registered trademark of BASF SE


Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Wiesław Sawicki et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 60(1), 153-158 (2005-04-26)
The purpose of this study was to work out a method of compression of floating pellets with verapamil hydrochloride (VH) in a dose of 40 mg. It was assumed that this form should reside in the stomach floating for several
Nizar Al-Zoubi et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 735-742 (2008-02-23)
Sustained-release of buspirone HCl (BUH) was attempted by spray drying after dissolving in two commercially available aqueous polymeric dispersions (Eudragit RS 30 D or Kollicoat SR 30 D) at five different drug:polymer ratios (1:1, 1:2, 1:3, 1:6 and 1:9). The
Sandra Strübing et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 69(2), 708-717 (2008-02-06)
The purpose of this study was to investigate the mechanism of floating and drug release behaviour of poly(vinyl acetate)-based floating tablets with membrane controlled drug delivery. Propranolol HCl containing tablets with Kollidon SR as an excipient for direct compression and



Global Trade Item Number

SKUGTIN
96329-500G04061833317785