96599
DL -4-Hydroxy-2-ketoglutaric acid lithium salt
≥90.0% (TLC)
Synonym(s):
4-Hydroxy-2-oxoglutaric acid lithium salt, DL-KHG Li
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About This Item
Empirical Formula (Hill Notation):
C5H6O6 · xLi+
CAS Number:
Molecular Weight:
162.10 (free acid basis)
MDL number:
UNSPSC Code:
12352106
NACRES:
NA.28
Beilstein/REAXYS Number:
1780096
Assay:
≥90.0% (TLC)
Form:
solid
Quality Segment
assay
≥90.0% (TLC)
form
solid
impurities
≤15.0% water, 3.9-8.4% lithium (anhydrous basis)
storage temp.
−20°C
SMILES string
OC(CC(=O)C(=O)O)C(=O)O
InChI
1S/C5H6O6/c6-2(4(8)9)1-3(7)5(10)11/h2,6H,1H2,(H,8,9)(H,10,11)
InChI key
WXSKVKPSMAHCSG-UHFFFAOYSA-N
Biochem/physiol Actions
DL-4-Hydroxy-2-ketoglutaric acid (DL-KHG) is an enzyme substrate for GOT (glutamic oxalacetic aminotransferase) and 2-Keto-4-hydroxyglutarate aldolase, which catalyzes the reversible cleavage of 2-keto-4-hydroxyglutarate yielding pyruvate plus glyoxylate; DL-KHG has been used in mass spectrometry for the rapid analysis of negatively charged water-soluble cellular metabolites.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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