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A2142

N-Acetyl-α-D-glucosamine 1-phosphate disodium salt

≥95% (TLC)

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About This Item

Linear Formula:
C8H14NO9PNa2
CAS Number:
31281-59-1
Molecular Weight:
345.15
NACRES:
NA.25
PubChem Substance ID:
24890630
UNSPSC Code:
12352201
MDL number:
MFCD00070180
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Quality Level

300

assay

≥95% (TLC)

form

powder

impurities

≤9% water (Karl Fischer)

color

white

solubility

water: 50 mg/mL, clear, colorless

cation traces

Na: 10.0-14.0% (Dry basis), P: 8.0-9.6% (dry basis)

storage temp.

−20°C

SMILES string

[Na].CC(=O)NC1C(O)C(O)C(CO)OC1OP(O)(O)=O

InChI

1S/C8H16NO9P.Na.H/c1-3(11)9-5-7(13)6(12)4(2-10)17-8(5)18-19(14,15)16;;/h4-8,10,12-13H,2H2,1H3,(H,9,11)(H2,14,15,16);;

InChI key

VFEAQNOAPUQCLS-UHFFFAOYSA-N

Related Categories

General description

N-Acetyl-D-glucosamine 1-phosphate (GlcNAc-1P) acts as a substrate for UDP-GlcNAc pyrophosphorylase to synthesize UDP-GlcNAc in the presence of UTP. GlcNAc-1P is a product of reverse pyrophosphorolysis of UDP-GlcNAc catalyzed by UDP-GlcNAc pyrophosphorylase.

Application

N-Acetyl-α-D-glucosamine 1-phosphate disodium salt has been used as a component of substrate solution for nucleotide triphosphate (NTP) transferases.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
0000436372
0000436372
0000423771
0000423751
0000423771

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A mechanism-inspired UDP-N-acetylglucosamine pyrophosphorylase inhibitor
Raimi OG, et al.
RSC medicinal chemistry, 1(1), 13-25 (2020)
Alexandra Deli et al.
The FEBS journal, 277(13), 2740-2753 (2010-05-25)
The genomes of Bacillus cereus and its closest relative Bacillus anthracis each contain two LmbE protein family homologs: BC1534 (BA1557) and BC3461 (BA3524). Only a few members of this family have been biochemically characterized including N-acetylglucosaminylphosphatidyl inositol (GlcNAc-PI), 1-D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins)
Measurement of Nucleotide Triphosphate Sugar Transferase Activity via Generation of Pyrophosphate
Maeda K, et al.
2013 Nurse's Drug Handbook, 5(8), e1450-e1450 (2015)

Global Trade Item Number

SKUGTIN
A2142-10MG04061832386706
A2142-25MG04061832386713
A2142-5MG04061832386720

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