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Merck
CN

A2628

L-Alanine β-naphthylamide

protease substrate

Synonym(s):

L-Alanine 2-naphthylamide

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About This Item

Empirical Formula (Hill Notation):
C13H14N2O
CAS Number:
Molecular Weight:
214.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352204
NACRES:
NA.83
EC Number:
211-956-5
MDL number:
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Quality Level

assay

≥98% (TLC)

form

powder

solubility

ethanol: 50 mg/mL, clear to slightly hazy

storage temp.

2-8°C

SMILES string

C[C@H](N)C(=O)Nc1ccc2ccccc2c1

InChI

1S/C13H14N2O/c1-9(14)13(16)15-12-7-6-10-4-2-3-5-11(10)8-12/h2-9H,14H2,1H3,(H,15,16)/t9-/m0/s1

InChI key

RQHPADKWNYTHOH-VIFPVBQESA-N

Application

L-Alanine Ǧ-naphthylamide has been used to determine the activity of alanine aminopeptidase (AAP) in blood samples. It may be used as a fluorescent substrate to assay neutral aminopeptidase (APN) activity in cultured human and mouse chondrocytes.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Anna Bizoń et al.
Environmental toxicology and pharmacology, 53, 74-80 (2017-05-16)
The effect of tobacco smoke on lipid peroxidation, the lipid profile and membrane-bound enzymatic activity in the first trimester of pregnancy was investigated. In the plasma of women with active exposure to tobacco smoke, we have found increased lipid peroxidation
Simone Cristina Yamasaki et al.
Regulatory peptides, 173(1-3), 47-54 (2011-10-11)
This study evaluated the hypothesis that neutral (APN) and dipeptidyl-IV (DPPIV) aminopeptidase activity levels would be critical for the susceptibility to arthritis in collagen-induced model (CIA). The macroscopic signs of arthritis in CIA rats were checked and peripheral blood, synovial
D R Buckler et al.
Biochemistry, 34(49), 15965-15978 (1995-12-12)
Formation of local structure and overall chain dimensions in the 124-residue, four-disulfide protein bovine pancreatic ribonuclease A (RNase A) under conditions favoring either the native or partially folded states have been studied by nonradiative excitation energy transfer measurements. Three RNase



Global Trade Item Number

SKUGTIN
A2628-1G04061826731659