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Merck
CN

B1893

8-Bromoguanosine

Synonym(s):

2-Amino-8-bromo-6-hydroxypurine riboside

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About This Item

Empirical Formula (Hill Notation):
C10H12BrN5O5
CAS Number:
Molecular Weight:
362.14
UNSPSC Code:
41106305
PubChem Substance ID:
EC Number:
223-677-6
MDL number:
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assay

≥99% (TLC)

form

solid

storage temp.

−20°C

SMILES string

NC1=Nc2c(nc(Br)n2[C@@H]3O[C@@H](CO)[C@H](O)[C@@H]3O)C(=O)N1

InChI

1S/C10H12BrN5O5/c11-9-13-3-6(14-10(12)15-7(3)20)16(9)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H3,12,14,15,20)/t2?,4?,5?,8-/m1/s1

InChI key

ASUCSHXLTWZYBA-RMAPPFHFSA-N



Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Carla B Mellough et al.
Stem cells translational medicine, 8(7), 694-706 (2019-03-28)
A major goal in the stem cell field is to generate tissues that can be utilized as a universal tool for in vitro models of development and disease, drug development, or as a resource for patients suffering from disease or
Leishmania amazonensis infection is reduced in macrophages treated with guanine ribonucleosides.
S Giorgio et al.
Acta tropica, 70(1), 119-122 (1998-08-26)
Rabindra Nath Das et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(19), 6008-6014 (2012-03-31)
Transparent self-standing supramolecular hydrogels were readily prepared by the potassium-ion-mediated self-organization of guanosine and 8-bromoguanosine whilst the individual components precipitated within a few hours. VT-NMR spectroscopy showed that bromoguanosine was a superior gelator compared to guanosine. XRD analysis showed that