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Merck
CN

B1893

8-Bromoguanosine

Synonym(s):

2-Amino-8-bromo-6-hydroxypurine riboside

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About This Item

Empirical Formula (Hill Notation):
C10H12BrN5O5
CAS Number:
4016-63-1
Molecular Weight:
362.14
UNSPSC Code:
41106305
PubChem Substance ID:
24891618
EC Number:
223-677-6
MDL number:
MFCD00037985

Key Documents

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InChI key

ASUCSHXLTWZYBA-RMAPPFHFSA-N

InChI

1S/C10H12BrN5O5/c11-9-13-3-6(14-10(12)15-7(3)20)16(9)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H3,12,14,15,20)/t2?,4?,5?,8-/m1/s1

SMILES string

NC1=Nc2c(nc(Br)n2[C@@H]3O[C@@H](CO)[C@H](O)[C@@H]3O)C(=O)N1

assay

≥99% (TLC)

form

solid

storage temp.

−20°C

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
084M4815V
086F4008
086F4006
086F4005

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Rabindra Nath Das et al.
Chemistry (Weinheim an der Bergstrasse, Germany), 18(19), 6008-6014 (2012-03-31)
Transparent self-standing supramolecular hydrogels were readily prepared by the potassium-ion-mediated self-organization of guanosine and 8-bromoguanosine whilst the individual components precipitated within a few hours. VT-NMR spectroscopy showed that bromoguanosine was a superior gelator compared to guanosine. XRD analysis showed that
Julia Dolinina et al.
American journal of physiology. Renal physiology, 311(5), F984-F990 (2016-09-30)
There is increasing evidence that the permeability of the glomerular filtration barrier (GFB) is partly regulated by a balance between the bioavailability of nitric oxide (NO) and that of reactive oxygen species (ROS). It has been postulated that normal or
Leishmania amazonensis infection is reduced in macrophages treated with guanine ribonucleosides.
S Giorgio et al.
Acta tropica, 70(1), 119-122 (1998-08-26)
Carla B Mellough et al.
Stem cells translational medicine, 8(7), 694-706 (2019-03-28)
A major goal in the stem cell field is to generate tissues that can be utilized as a universal tool for in vitro models of development and disease, drug development, or as a resource for patients suffering from disease or
Akimasa Matsugami et al.
The FEBS journal, 274(14), 3545-3556 (2007-06-15)
The structure of human telomeric DNA is controversial; it depends upon the sequence contexts and the methodologies used to determine it. The solution structure in the presence of K(+) is particularly interesting, but the structure is yet to be elucidated
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