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C144

1-(3-Chlorophenyl)biguanide hydrochloride

solid

Synonym(s):

1-(m-Chlorophenyl)biguanide hydrochloride, N-(3-Chlorophenyl)imidodicarbonimidic diamide hydrochloride, m-CPBG hydrochloride

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About This Item

Linear Formula:
ClC6H4NHC(NH)NHC(NH)NH2 · HCl
CAS Number:
2113-05-5
Molecular Weight:
248.11
NACRES:
NA.77
PubChem Substance ID:
24278089
UNSPSC Code:
12352202
MDL number:
MFCD00053019
Form:
solid
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form

solid

color

white

mp

190-194 °C (lit.)

solubility

H2O: soluble

SMILES string

Cl[H].NC(=N)NC(=N)Nc1cccc(Cl)c1

InChI

1S/C8H10ClN5.ClH/c9-5-2-1-3-6(4-5)13-8(12)14-7(10)11;/h1-4H,(H6,10,11,12,13,14);1H

InChI key

FOWAIJYHRWFTHR-UHFFFAOYSA-N

Gene Information

human ... HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242)

Biochem/physiol Actions

Very potent 5-HT3 serotonin receptor agonist.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SLCD2737
SLCB1913
SLBS8107
SLBN9992V
SLBF8520V

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Zachary A Rodd et al.
The Journal of pharmacology and experimental therapeutics, 321(3), 1003-1012 (2007-02-28)
Studies from our laboratory indicated that local perfusion of the ventral tegmental area (VTA) with a serotonin-3 (5-HT(3)) receptor agonist increased dopamine (DA) neuronal activity and that the self-infusion of ethanol (EtOH) and cocaine into the posterior VTA could be
Wen Liu et al.
Alcohol (Fayetteville, N.Y.), 40(3), 167-176 (2007-04-10)
The objectives of the present study were to (a) examine the effects of activating serotonin-3 (5-HT3) receptors on dopamine (DA) release in the anterior and posterior ventral tegmental area (VTA) of Wistar rats and (b) determine if there are differences
Borna Payandemehr et al.
Epilepsy research, 101(3), 217-227 (2012-05-15)
Citalopram is a selective serotonin reuptake inhibitor (SSRI), widely used in the treatment of depressive disorders. It has been shown that citalopram affects seizure susceptibility. Although the exact mechanism of these effects are not yet fully understood, recent data suggest
View All Related Papers

Global Trade Item Number

SKUGTIN
C144-500MG04061833467619