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Merck
CN

C1506

Cytidine 5′-triphosphate disodium salt

≥95%, P2X4 purinergic receptor agonist, powder

Synonym(s):

CTP

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About This Item

Empirical Formula (Hill Notation):
C9H14N3Na2O14P3
CAS Number:
Molecular Weight:
527.12
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
252-849-3
MDL number:
Assay:
≥95%
Form:
powder
Quality level:
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Product Name

Cytidine 5′-triphosphate disodium salt, ≥95%

Quality Level

assay

≥95%

form

powder

storage temp.

−20°C

SMILES string

[Na+].[Na+].NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]2O

InChI

1S/C9H16N3O14P3.2Na/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18);;/q;2*+1/p-2/t4-,6-,7-,8-;;/m1../s1

InChI key

NFQMDTRPCFJJND-WFIJOQBCSA-L

General description

Cytidine 5′-triphosphate is a nucleoside triphosphate with a pyrimidine ring. It is present in RNA.

Application

Cytidine 5′-triphosphate disodium salt has been used:
  • for the conversion of adenosine monophosphate (AMP) to adenosine diphosphate (ADP) in luminometry analysis
  • in the preparation of ribonucleotide 5′-triphosphate precursors stocks for large-scale RNA synthesis
  • to perform in vitro transcription

Biochem/physiol Actions

Cytidine 5′-triphosphate (CTP) prevents the action of aspartate carbamoyltransferase. This enzyme participates in pyrimidine biosynthesis. Like adenosine triphosphate (ATP), CTP serves as a molecule of high energy. It acts as a coenzyme in glycerophospholipid biosynthesis and protein glycosylation.
P2X4 purinergic receptor agonist.

Features and Benefits

This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

235.4 °F - closed cup

flash_point_c

113 °C - closed cup

ppe

Eyeshields, Gloves, type N95 (US)


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Determining structures of RNA aptamers and riboswitches by X-ray crystallography
Nucleosides, nucleotides & nucleic acids, 135-163 (2009)
Genetics (2016)
Secretion From Dense Granules
Platelets and megakaryocytes, 83-93 (2004)
Methods in Molecular Biology, 89-89 (2018)
Scientific and Technical Terms in Bioengineering and Biological Engineering (2018)

Global Trade Item Number

SKUGTIN
C1506-10MG04061833467633
C1506-25MG04061833467664
C1506-250MG04061833467657
C1506-1G04061833467640
C1506-100MG04061832081434

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