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D0400

9,11-Dideoxy-9α,11α-epoxymethanoprostaglandin F2α

Synonym(s):

U44069

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About This Item

Empirical Formula (Hill Notation):
C21H34O4
CAS Number:
56985-32-1
Molecular Weight:
350.49
NACRES:
NA.77
PubChem Substance ID:
24893231
UNSPSC Code:
12352211
MDL number:
MFCD00135237
Form:
liquid
Quality level:
200
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description

solution in methyl acetate

Quality Level

200

form

liquid

shipped in

dry ice

storage temp.

−20°C

SMILES string

CCCCC[C@H](O)\C=C\[C@H]1[C@@H]2CO[C@@H](C2)[C@@H]1C\C=C/CCCC(O)=O

InChI

1S/C21H34O4/c1-2-3-6-9-17(22)12-13-18-16-14-20(25-15-16)19(18)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24)/b7-4-,13-12+/t16-,17-,18-,19+,20-/m0/s1

InChI key

DJKDIKIDYDXHDD-IGUVKOCZSA-N

Related Categories

Biochem/physiol Actions

Prostaglandin F2α analogue; thromboxane A2/prostaglandin H2 mimetic.

Disclaimer

Supply conditions do not apply to the regions and states of Brazil: North, Northeast, Mato Grosso do Sul, Mato Grosso, and Rio Grande do Sul.

pictograms

FlameExclamation mark
GHS02,GHS07

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

EUH066

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

8.6 °F

flash_point_c

-13 °C

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number
0000482776
0000482775
0000482775
0000482776
0000330722

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Zhucheng Chen et al.
Biochemistry, 42(9), 2542-2551 (2003-03-05)
Thromboxane synthase is a hemethiolate enzyme that catalyzes the isomerization of prostaglandin H2 to thromboxane A2. We report the first resonance Raman (RR) spectra of recombinant human thromboxane synthase (TXAS) in both the presence and the absence of substrate analogues
S M Dyer et al.
Clinical and experimental pharmacology & physiology, 25(3-4), 246-251 (1998-05-20)
1. 5-Hydroxytryptamine (5-HT) exerts both contractile and relaxant effects in the marmoset isolated aorta, actions that are unaffected by the 5-HT2 antagonist ketanserin. The aim of the present study was to define the receptors mediating the contractile activity of 5-HT
M E Chapman et al.
Poultry science, 85(4), 777-786 (2006-04-18)
The pathogenesis of pulmonary hypertension remains incompletely understood. Many factors have been implicated; however, there has been great interest in the potent pulmonary vasoconstrictor serotonin (5-HT) due to episodes of primary pulmonary hypertension in humans triggered by serotoninergic appetite-suppressant drugs.
K R Olson et al.
The Journal of experimental zoology, 286(6), 606-614 (2000-04-15)
Isolated vessels from four elasmobranchs, yellow stingray (Urolophus jamaicensis), clearnose skate (Raja eglanteria), ghost shark (Hydrolagus novaezelandiae), and spiny dogfish (Squalus acanthias), were examined for the presence of spontaneous contractions (SC). SC were observed in otherwise unstimulated dorsal aortas (DA)
J A Scott et al.
Canadian journal of physiology and pharmacology, 77(2), 89-95 (1999-10-27)
Nonadrenergic noncholinergic (NANC) mediated vasodilation may contribute to the maintenance of low pulmonary vascular tone. The NANC neurotransmitters, nitric oxide (NO) and the sensory neuropeptides, substance P and calcitonin gene related peptide (CGRP), were investigated as possible mediators of NANC
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Global Trade Item Number

SKUGTIN
D0400-10MG04061832785288
D0400-5MG04061833557655
D0400-1MG04061826674376

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