Skip to Content
Merck
CN

Key Documents

View All Documentation

EPS001

HAT Activator, CTPB

A potent activator of HAT (histone acetyltransferase)

Synonym(s):

Benzamide, N-[4-chloro-3-(trifluoromethyl)phenyl]-2-ethoxy-6-pentadecyl, CTPB, CTPB (enzyme activator), CTPB (enzyme inhibitor), N-(4-Chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C31H43ClF3NO2
CAS Number:
586976-24-1
Molecular Weight:
554.13
UNSPSC Code:
12352200
Assay:
≥97% (H-NMR)
Storage condition:
desiccated, protect from light
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

assay

≥97% (H-NMR)

storage condition

desiccated, protect from light

color

white to off-white

solubility

DMSO: soluble

storage temp.

−20°C

InChI

1S/C31H43ClF3NO2/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-18-24-19-17-20-28(38-4-2)29(24)30(37)36-25-21-22-27(32)26(23-25)31(33,34)35/h17,19-23H,3-16,18H2,1-2H3,(H,36,37)

InChI key

OYBMVMAXKOGYDC-UHFFFAOYSA-N

General description

(N-(4-chloro-3-trifluoromethyl-phenyl)-2-ethoxy-6-pentadecyl-benzamide) or CTPB, which is a non-polar compound, has been shown to enhance the neurite growth and survival of neuronal cell lines.
A potent activator of p300 HAT (histone acetyltransferase), but not of PCAF (p300/CBP-associated factor) HAT activities.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.

If you need assistance, please contact Customer Support

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Small molecule modulators of histone acetyltransferase p300
Karanam B et al.
The Journal of Biological Chemistry (2003)
A small molecule activator of p300/CBP histone acetyltransferase promotes survival and neurite growth in a cellular model of Parkinson?s disease
Shane VH et al.
Neurotoxicity Research, 30(3), 510-520 (2016)
Shufeng Li et al.
OncoTargets and therapy, 13, 12383-12395 (2020-12-11)
Cervical squamous cell carcinoma (CSCC) is responsible for 80-85% of cervical cancer. Cyclin B1 (CCNB1) represents a hub gene during the development of cervical cancer. However, the oncogenic role of CCNB1 in CSCC remains unclear. Our study aims to explore

Global Trade Item Number

SKUGTIN
EPS001-1MG04061833609545
EPS001-5MG04061833609552