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About This Item
Empirical Formula (Hill Notation):
C11H18N4O5
CAS Number:
Molecular Weight:
286.28
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
assay
≥97% (HPLC)
form
solid
technique(s)
NMR: suitable
storage temp.
−20°C
SMILES string
NCC(=O)N1CCCC1C(=O)NCC(=O)NCC(O)=O
InChI
1S/C11H18N4O5/c12-4-9(17)15-3-1-2-7(15)11(20)14-5-8(16)13-6-10(18)19/h7H,1-6,12H2,(H,13,16)(H,14,20)(H,18,19)
InChI key
PEZMQPADLFXCJJ-UHFFFAOYSA-N
Biochem/physiol Actions
Inhibitor of dipeptidyl peptidase IV. Inhibits entry of HIV-1 or HIV-2 into T lymphoblastoid and monocytoid cell lines.
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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Abil E Aliev et al.
The journal of physical chemistry. B, 114(38), 12358-12375 (2010-09-10)
Experimental NMR verification of MD simulations using 12 different force fields (AMBER, CHARMM, GROMOS, and OPLS-AA) and 5 different water models has been undertaken to identify reliable MD protocols for structure and dynamics elucidations of small open chain peptides containing
[Effect of simple proline-containing peptides on the functional activity of the anticoagulant system and primary homeostasis].
I P Ashmarin et al.
Biulleten' eksperimental'noi biologii i meditsiny, 125(5), 496-499 (1998-06-30)
I P Ashmarin et al.
Biochemistry. Biokhimiia, 63(2), 119-124 (1998-06-02)
Our own data and data from the literature on the regulatory role of the simplest proline-containing peptides GP, PG, PGP, GPGG, and cyclic-PG are summarized. These peptides are involved in homeostasis of gastric mucosa and the anticoagulant and fibrinolytic potential