G6011
Gly-Pro-Gly-Gly
≥97% (HPLC)
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About This Item
Empirical Formula (Hill Notation):
C11H18N4O5
CAS Number:
Molecular Weight:
286.28
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Assay
≥97% (HPLC)
form
solid
technique(s)
NMR: suitable
storage temp.
−20°C
SMILES string
NCC(=O)N1CCCC1C(=O)NCC(=O)NCC(O)=O
InChI
1S/C11H18N4O5/c12-4-9(17)15-3-1-2-7(15)11(20)14-5-8(16)13-6-10(18)19/h7H,1-6,12H2,(H,13,16)(H,14,20)(H,18,19)
InChI key
PEZMQPADLFXCJJ-UHFFFAOYSA-N
Biochem/physiol Actions
Inhibitor of dipeptidyl peptidase IV. Inhibits entry of HIV-1 or HIV-2 into T lymphoblastoid and monocytoid cell lines.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
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Abil E Aliev et al.
The journal of physical chemistry. B, 114(38), 12358-12375 (2010-09-10)
Experimental NMR verification of MD simulations using 12 different force fields (AMBER, CHARMM, GROMOS, and OPLS-AA) and 5 different water models has been undertaken to identify reliable MD protocols for structure and dynamics elucidations of small open chain peptides containing
Tsonko M Kolev
Protein and peptide letters, 15(7), 713-718 (2008-09-11)
The IR-spectroscopic and structural elucidation of tetrapeptide glycyl-(L)-prolyl-glycyl-glycine and its hydrogensquarate was performed by employing linear-polarized IR-spectroscopy of oriented colloid suspensions in nematic host as well as mass spectrometry. Quantum-chemical ab initio calculations were carried out in order to evaluate
V E Pastorova et al.
Izvestiia Akademii nauk. Seriia biologicheskaia, (3)(3), 390-394 (1998-06-30)
Anticoagulant, fibrinolytic, and fibrin-depolymerization effects were revealed during in vitro study of five proline-containing peptides (Gly-Pro, Trp-Pro, Pro-Gly, Gly-Pro-Gly-Gly, and Pro-Gly-Pro) in the concentration range 10(-9) to 10(-1) mg/ml. Intravenous injection of Trp-Pro and Pro-Gly into white rats at 250
[Effect of simple proline-containing peptides on the functional activity of the anticoagulant system and primary homeostasis].
I P Ashmarin et al.
Biulleten' eksperimental'noi biologii i meditsiny, 125(5), 496-499 (1998-06-30)
I P Ashmarin et al.
Biochemistry. Biokhimiia, 63(2), 119-124 (1998-06-02)
Our own data and data from the literature on the regulatory role of the simplest proline-containing peptides GP, PG, PGP, GPGG, and cyclic-PG are summarized. These peptides are involved in homeostasis of gastric mucosa and the anticoagulant and fibrinolytic potential
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