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Merck
CN

H2255

5-Hydroxyindole-3-acetic acid (dicyclohexylammonium) salt

crystalline, ≥98% (TLC)

Synonym(s):

5-HIAA

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About This Item

Empirical Formula (Hill Notation):
C10H9NO3 · C12H23N
CAS Number:
Molecular Weight:
372.50
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
Assay:
≥98% (TLC)
Form:
crystalline
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assay

≥98% (TLC)

form

crystalline

color

white

storage temp.

−20°C

SMILES string

C1CCC(CC1)NC2CCCCC2.OC(=O)Cc3c[nH]c4ccc(O)cc34

InChI

1S/C12H23N.C10H9NO3/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12;12-7-1-2-9-8(4-7)6(5-11-9)3-10(13)14/h11-13H,1-10H2;1-2,4-5,11-12H,3H2,(H,13,14)

InChI key

NIDSGTAJKGNSEN-UHFFFAOYSA-N

Biochem/physiol Actions

Major serotonin metabolite.

Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Jurjen J Luykx et al.
PloS one, 7(2), e30497-e30497 (2012-02-09)
Animal studies have revealed seasonal patterns in cerebrospinal fluid (CSF) monoamine (MA) turnover. In humans, no study had systematically assessed seasonal patterns in CSF MA turnover in a large set of healthy adults. Standardized amounts of CSF were prospectively collected
ENETS Consensus Recommendations for the Standards of Care in Neuroendocrine Neoplasms: Follow-Up and Documentation.
U Knigge et al.
Neuroendocrinology, 105(3), 310-319 (2017-02-22)
Sofia Raitsin et al.
Brain research, 1666, 1-10 (2017-04-25)
Recent human brain imaging studies implicate dysregulation of monoamine oxidase-A (MAO-A), in particular in the prefrontal cortex (PFC) and anterior cingulate cortex (ACC), in the development of major depressive disorder (MDD). This study investigates the influence of four alterations underlying
Xue Tao et al.
International journal of molecular sciences, 21(4) (2020-02-27)
In the pathology-oriented study of depression, inflammation hypothesis has received increasing attention for recent years. To mimic the depressive state caused by inflammation, rodents injected intraperitoneally with lipopolysaccharide (LPS) are usually used to stimulate an immune response. However, the dose
Ronghua Fan et al.
Environmental science and pollution research international, 26(21), 22040-22050 (2019-05-31)
Exposure to fine particulate matter (PM2.5) could induce lung impairment aggravation. Moreover, endogenous substances are known to play a significant role in lung impairment. Therefore, the research objectives was to investigate the influence of PM2.5-induced lung impairment on the levels

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