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Merck
CN

H3647

Methyl 4-hydroxybenzoate

BioReagent, suitable for insect cell culture

Synonym(s):

p-Hydroxybenzoic acid methyl ester, Methyl paraben, NIPAGIN

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About This Item

Linear Formula:
HOC6H4CO2CH3
CAS Number:
Molecular Weight:
152.15
UNSPSC Code:
12352207
NACRES:
NA.75
PubChem Substance ID:
EC Number:
202-785-7
Beilstein/REAXYS Number:
509801
MDL number:
Assay:
≥99.0% (HPLC)
Form:
powder or crystals
Quality level:
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biological source

synthetic

Quality Level

product line

BioReagent

assay

≥99.0% (HPLC)

form

powder or crystals

technique(s)

cell culture | insect: suitable

mp

125-128 °C (lit.)

solubility

ethanol: 50 mg/mL, clear, colorless

SMILES string

COC(=O)c1ccc(O)cc1

InChI

1S/C8H8O3/c1-11-8(10)6-2-4-7(9)5-3-6/h2-5,9H,1H3

InChI key

LXCFILQKKLGQFO-UHFFFAOYSA-N

Gene Information

rat ... Ar(24208)

General description

Parabens are ester derivatives of hydroxybenzoic acid. Methyl 4-hydroxybenzoate is a short-chain paraben, suitable for applications in food. It is found in cloudberry, white wine, yellow passion fruit, and bourbon vanilla.

Application

Methyl 4-hydroxybenzoate has been used:
  • to wash mites from the cells of Apis mellifera workers preceding the harvest of mite saliva
  • as a component of grape/apple juice agar plates to culture Drosophila for the extraction of ovaries/embryos
  • in studies on sterol hormones such as testosterone biosynthesis



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pictograms

Environment

hcodes

Hazard Classifications

Aquatic Chronic 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

334.4 °F

flash_point_c

168 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Preservatives: Food Use
Garcia RG, et al.
Encyclopedia of Food and Health, 505-509 (2016)
Mousumee Khan et al.
Nutrients, 11(5) (2019-05-01)
Resveratrol has gained widespread scientific attention due to its ability to significantly extend the lifespan of yeast. However, research on the efficacy of resveratrol on lifespan extension has yielded mixed results in animal studies, making resveratrol a contentious subject. In
Yi Zhang et al.
Journal of economic entomology, 112(2), 505-514 (2018-09-17)
The Varroa destructor (Acari Varroidae) mite is a serious threat to honey bee due to hemolymph feeding and virus transmission. Mite salivary proteins are involved in these interactions. However, the salivary secretome has not been previously characterized. In this paper



Global Trade Item Number

SKUGTIN
H3647-100G04061833793695
H3647-1KG04061833793725