I4375
Inosine 5′-diphosphate sodium salt
≥96%
Synonym(s):
IDP
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About This Item
Empirical Formula (Hill Notation):
C10H14N4O11P2
CAS Number:
Molecular Weight:
428.19
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Assay:
≥96%
Biological source:
microbial
Form:
powder
Solubility:
water: 50 mg/mL, clear to very slightly hazy, colorless
Storage temp.:
−20°C
biological source
microbial
Quality Level
assay
≥96%
form
powder
solubility
water: 50 mg/mL, clear to very slightly hazy, colorless
storage temp.
−20°C
SMILES string
[Na+].[Na+].[Na+].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP([O-])(=O)OP([O-])([O-])=O)n2cnc3C(=O)NC=Nc23
InChI
1S/C10H14N4O11P2.3Na/c15-6-4(1-23-27(21,22)25-26(18,19)20)24-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,11,12,17)(H2,18,19,20);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1
InChI key
CPIQGMJSIPVOOS-MSQVLRTGSA-K
Application
Inosine 5′-diphosphate sodium salt has been used for hystoenzymatic demonstration of nucleoside diphosphatase (NDPase).
Preparation Note
Prepared from muscle or bacterial ADP.
signalword
Warning
hcodes
Hazard Classifications
STOT SE 2
target_organs
Eyes,Central nervous system
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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John A Duley et al.
Therapeutic drug monitoring, 27(5), 647-654 (2005-09-22)
Metabolism of thiopurine drugs--azathioprine, 6-mercaptopurine, and 6-thioguanine--has provided a powerful pharmacogenetic model incorporating polymorphism of the enzyme thiopurine methyltransferase (TPMT) and the primary active metabolite, thioguanine nucleotide (TGN). However, a sense of uncertainty about the usefulness of TGNs and other
Increased number of microglia in the brain of severe combined immunodeficient (SCID) mice
Lorke DE, et al.
Histochemistry and Cell Biology, 130(4), 693-697 (2008)
Satoko Ohkubo et al.
European journal of pharmacology, 577(1-3), 35-43 (2007-09-20)
In C6 glioma cells, adenine nucleotides, especially AMP, and adenosine inhibited cell proliferation in time- and concentration-dependent manners. alpha,beta-methylene-ADP, an ecto-5'-nucleotidase inhibitor, suppressed the hydrolysis of AMP and reversed the inhibition of cell growth induced by AMP but not by
Global Trade Item Number
| SKU | GTIN |
|---|---|
| I4375-25MG | 04061833856741 |
| I4375-100MG | 04061833856734 |
| I4375-500MG | 04061833856758 |