I9890
m-Iodobenzylguanidine hemisulfate salt
≥98% (HPLC and TLC), ADP ribosylation inhibitor
Synonym(s):
MIBG
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About This Item
Linear Formula:
C8H10IN3 · 1/2H2SO4
CAS Number:
Molecular Weight:
324.13
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC and TLC)
Quality level:
Product Name
m-Iodobenzylguanidine hemisulfate salt, ≥98% (HPLC and TLC)
Quality Level
assay
≥98% (HPLC and TLC)
impurities
<0.5% Free iodobenzylamine
storage temp.
2-8°C
SMILES string
OS(O)(=O)=O.NC(=N)NCc1cccc(I)c1.NC(=N)NCc2cccc(I)c2
InChI
1S/2C8H10IN3.H2O4S/c2*9-7-3-1-2-6(4-7)5-12-8(10)11;1-5(2,3)4/h2*1-4H,5H2,(H4,10,11,12);(H2,1,2,3,4)
InChI key
XNACDNPGABUBFR-UHFFFAOYSA-N
Biochem/physiol Actions
Antitumor agent which inhibits ADP ribosylation.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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L A Smets et al.
Cancer chemotherapy and pharmacology, 21(1), 9-13 (1988-01-01)
Meta-iodo-benzylguanidine (MIBG) is an analogue of the neurotransmitter norepinephrine. In its radioiodinated form, MIBG is clinically used as a tumor-targeted radiopharmaceutical in the diagnosis and treatment of adrenergic tumors. The potential cytotoxicity of the unlabeled drug was tested. MIBG appeared
Adrien Lebasnier et al.
European journal of nuclear medicine and molecular imaging, 42(7), 1043-1051 (2015-01-30)
The aim of this study was to determine the potential diagnostic value of regional myocardial adrenergic (123)I-metaiodobenzylguanidine (MIBG) single photon emission computed tomography (SPECT) imaging to identify patients with Lewy body diseases (LBD+). Sixty-four consecutive patients who underwent cardiac (123)I-MIBG
Yunlong Zan et al.
Molecular imaging, 14, 373-384 (2015-07-15)
The objective of this work was to evaluate the sympathetic nervous system and structure remodeling during the progression of heart failure in a rodent model using dynamic cardiac single-photon emission computed tomography (SPECT). The spontaneously hypertensive rat (SHR) model was
Global Trade Item Number
| SKU | GTIN |
|---|---|
| I9890-25MG | 04061832722818 |
| I9890-5MG | 04061832722825 |