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Merck
CN

P0314

Prostaglandin F methyl ester

~5 mg/mL in methyl acetate, ≥95% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C21H36O5
CAS Number:
Molecular Weight:
368.51
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
201-185-2
MDL number:
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assay

≥95% (HPLC)

concentration

~5 mg/mL in methyl acetate

storage temp.

−20°C

SMILES string

CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(=O)OCC

InChI

1S/C22H38O5/c1-3-5-8-11-17(23)14-15-19-18(20(24)16-21(19)25)12-9-6-7-10-13-22(26)27-4-2/h6,9,14-15,17-21,23-25H,3-5,7-8,10-13,16H2,1-2H3/b9-6-,15-14+/t17-,18+,19+,20-,21+/m0/s1

InChI key

KRDFNHLEMLCWKD-GWSKAPOCSA-N

Biochem/physiol Actions

Constricts an isolated human smooth muscle; methyl ester form of prostaglandin F2α which is a luteolytic prostaglandin (induces parturition; pulmonary vasoconstrictor).

Packaging

Packaged under Argon.


pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

15.0 °F

flash_point_c

-9.45 °C

ppe

Eyeshields, Faceshields, Gloves

Regulatory Information

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B V Praveen et al.
International journal of clinical pharmacology, therapy, and toxicology, 30(1), 7-12 (1992-01-01)
A prospective randomized, controlled study was done to compare the efficacy and safety of 15(s) 15 Me PGF2 alpha intravesical instillation and 1% alum vesical irrigation in the control of vesical hematuria which persisted even after continuous bladder irrigation with
The ocular hypotensive effects and side effects of prostaglandins on the eyes of experimental animals.
L Z Bito et al.
Progress in clinical and biological research, 312, 349-368 (1989-01-01)
Zhonghua fu chan ke za zhi, 25(1), 31-34 (1990-01-01)
Abortion was attempted in 316 healthy women in early pregnancy within 7 weeks with the RU486 alone (600mg in a single oral dose) or in combination with a PG (15-dl-methyl-PGF2 alpha-methyl-ester) 1 mg suppository. The result of using RU 486



Global Trade Item Number

SKUGTIN
P0314-1MG04061838065100