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Merck
CN

P0314

Prostaglandin F methyl ester

~5 mg/mL in methyl acetate, ≥95% (HPLC)

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About This Item

Empirical Formula (Hill Notation):
C21H36O5
CAS Number:
Molecular Weight:
368.51
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
201-185-2
MDL number:
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assay

≥95% (HPLC)

concentration

~5 mg/mL in methyl acetate

storage temp.

−20°C

SMILES string

CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(=O)OCC

InChI

1S/C22H38O5/c1-3-5-8-11-17(23)14-15-19-18(20(24)16-21(19)25)12-9-6-7-10-13-22(26)27-4-2/h6,9,14-15,17-21,23-25H,3-5,7-8,10-13,16H2,1-2H3/b9-6-,15-14+/t17-,18+,19+,20-,21+/m0/s1

InChI key

KRDFNHLEMLCWKD-GWSKAPOCSA-N

Biochem/physiol Actions

Constricts an isolated human smooth muscle; methyl ester form of prostaglandin F2α which is a luteolytic prostaglandin (induces parturition; pulmonary vasoconstrictor).

Packaging

Packaged under Argon.


pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

Storage Class

3 - Flammable liquids

wgk

WGK 2

flash_point_f

15.0 °F

flash_point_c

-9.45 °C

ppe

Eyeshields, Faceshields, Gloves

Regulatory Information

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The ocular hypotensive effects and side effects of prostaglandins on the eyes of experimental animals.
L Z Bito et al.
Progress in clinical and biological research, 312, 349-368 (1989-01-01)
Zhonghua fu chan ke za zhi, 25(1), 31-34 (1990-01-01)
Abortion was attempted in 316 healthy women in early pregnancy within 7 weeks with the RU486 alone (600mg in a single oral dose) or in combination with a PG (15-dl-methyl-PGF2 alpha-methyl-ester) 1 mg suppository. The result of using RU 486
B Wu et al.
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 13(2), 177-180 (1997-05-01)
The effect of 15-Mt-PGF2 alpha on CCl4-induced injury of primary cultured hepatocytes was studied. 15-Mt-PGF2 alpha treatment (2 mg/L) significantly decreased CCl4 (10 mmol/L)-induced damages of primary cultured rat heptocytes as indicated by decreases GPT and GOT leakage and LPO



Global Trade Item Number

SKUGTIN
P0314-1MG04061838065100