Anti-Purinergic Receptor P2Y₁₂ antibody produced in rabbit

Purinergic receptor or platelet adenosine 5′-diphosphate (ADP) receptor P2Y12 is a G-protein-coupled receptor. The gene encoding it is localized on human chromosome 3q25.1.

peptide corresponding to amino acid residues 125-142 of human P2Y₁₂. This epitope is highly homologous in rat and mouse (16/18 residues identical).

Anti-Purinergic Receptor P2Y12 antibody produced in rabbit has been used in Western blotting.

Purinergic receptor or platelet adenosine 5′-diphosphate (ADP) receptor P2Y12 has a role in platelet aggregation induced by ADP. Dysfunctional mutations in the protein have been linked with bleeding disorders. Studies have indicated that mice deficient in the P2Y12 receptor show decreased tumor metastasis.

Lyophilized from phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 0.05% sodium azide.

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