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About This Item
NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), IHC, WB
Citations:
5
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, rat, mouse
technique(s)
immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... GBAS(2631)
General description
NIPSNAP2 (nipsnap homolog 2) belongs to the NIPSNAP family. It is also known as GBAS (glioblastoma amplified sequence). It is located in the mitochondrial inner membrane space. It is highly expressed in skeletal muscle and heart. GBAS codes for a protein, that has tyrosine phosphorylation sites and a transmembrane domain. It is co-amplified with EGFR (epidermal growth factor receptor gene). It is located on chromosome 7p11.2.
Immunogen
a 14 amino acid peptide near the center of human NIPSNAP2.
Biochem/physiol Actions
NIPSNAP2 (nipsnap homolog 2) plays a major role in transcriptional regulation via L-type Ca2+ channels.
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide
Other Notes
The action of this antibody can be blocked using blocking peptide SBP4953.
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Storage Class
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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De novo 393 kb microdeletion of 7p11.2 characterized by aCGH in a boy with psychomotor retardation and dysmorphic features
Varvagiannis K, et al.
Meta Gene, 2, 274-282 (2014)
NIP-SNAP-1 and -2 mitochondrial proteins are maintained by heat shock protein 60
Yamamoto S, et al.
Biochemical and Biophysical Research Communications, 483(3), 917-922 (2017)
Regulation of CREB signaling through L-type Ca2+ channels by Nipsnap-2
Brittain JM, et al.
Channels (Austin, Tex.), 6(2), 94-102 (2012)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SBP4953-0.05MG | 04061832164984 |
| PRS4953-100UG | 04061831490992 |