S8260
Salbutamol
≥96% (GC), powder, β2 adrenoceptor agonist
Synonym(s):
α-[(tert-Butylamino)methyl]-4-hydroxy-m-xylene-α,α′-diol, Albuterol
Sign In to View Organizational & Contract Pricing.
Select a Size
About This Item
Empirical Formula (Hill Notation):
C13H21NO3
CAS Number:
Molecular Weight:
239.31
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
242-424-0
MDL number:
Beilstein/REAXYS Number:
6405698
Quality level:
Product Name
Salbutamol,
Quality Level
solubility
methanol: complete 50 mg/ml, clear, colorless to yellow
originator
GlaxoSmithKline
SMILES string
CC(C)(C)NCC(O)c1ccc(O)c(CO)c1
InChI
1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3
InChI key
NDAUXUAQIAJITI-UHFFFAOYSA-N
Gene Information
human ... ADRB2(154)
Looking for similar products? Visit Product Comparison Guide
Related Categories
Application
Salbutamol was administered to primate model to study the bronchoconstriction in chronic allergic asthma.20 Salbutamol was used as a standard for rapid pharmacokinetic screening of human plasma samples using HPLC.21
Biochem/physiol Actions
β2-adrenoceptor agonist
Salbutamol is a β2 adrenoceptor agonist with short acting bronchodilation and anti-inflammatory effects. It relaxes the airway smooth muscles and inhibits bronchoconstriction induced by adenosine-5′ -monophosphate (AMP).1 Salbutamol is particularly effective in treatment of asthma as it provides immediate relief.2
Features and Benefits
This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Skin Sens. 1B
Storage Class
11 - Combustible Solids
wgk
WGK 2
ppe
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
监管及禁止进口产品
This item has
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Huib A M Kerstjens et al.
The Lancet. Respiratory medicine, 3(5), 367-376 (2015-02-16)
In patients with severe asthma, tiotropium improves lung function and exacerbation risk when added to high-dose inhaled corticosteroids plus long-acting β2 agonists. We aimed to assess the safety and efficacy of tiotropium in patients with moderate asthma who were symptomatic
James Fingleton et al.
The Journal of allergy and clinical immunology, 136(3), 601-609 (2015-03-10)
Asthma and chronic obstructive pulmonary disease (COPD) are heterogeneous disorders encompassing different phenotypes of airflow obstruction, which might differ in their response to treatment. The aim of this study was to determine distinct phenotypes comprising the syndromes of asthma and
M Reza Maleki-Yazdi et al.
Respiratory medicine, 108(12), 1752-1760 (2014-12-03)
Combinations of inhaled long-acting bronchodilator therapies such as muscarinic antagonists and β2-agonists may be more effective than monotherapy in the treatment of chronic obstructive pulmonary disease (COPD). This study was a 24-week, Phase III, multicenter, randomized, blinded, double-dummy, parallel-group study
Rachel A Matt et al.
Frontiers in molecular biosciences, 10, 1214102-1214102 (2023-09-04)
Noradrenergic projections from the brainstem locus coeruleus drive arousal, attentiveness, mood, and memory, but specific adrenoceptor (AR) function across the varied brain cell types has not been extensively characterized, especially with agonists. This study reports a pharmacological analysis of brain
Kirti Singh et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 168, 115763-115763 (2023-10-23)
Asthma and other airway obstructive disorders are characterized by heightened inflammation and excessive airway epithelial cell reactive oxygen species (ROS), which give rise to a highly oxidative environment. After decades of use, β2-adrenergic receptor (β2AR) agonists remain at the forefront
Global Trade Item Number
| SKU | GTIN |
|---|---|
| S8260-100MG | 04061836960629 |
| S8260-250MG | 04061836960636 |
| S8260-25MG | 04061836960643 |
| S8260-50MG | 04061836960650 |
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service