SAB3500204
Anti-CX3CR1 antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
Synonym(s):
Anti-V28
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About This Item
Conjugate:
unconjugated
Clone:
polyclonal
Application:
ELISA (i), FACS, IF, IHC, WB
Citations:
5
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
predicted mol wt 50 kDa
species reactivity
mouse, human, rat
technique(s)
flow cytometry: suitable, immunofluorescence: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... CX3CR1(1524)
General description
C-X3-C motif chemokine receptor 1(CX3CR1) is a seven transmembrane domain G‐protein‐coupled receptor. The gene is located on human chromosome 3p22.2. CX3CR1 is expressed in different types of inflammatory cells.
Immunogen
CX3CR1 antibody was raised against a peptide corresponding to amino acids 2 to 21 of human CX3CR1. The sequence differs from those of mouse and rat CX3CR1 by four amino acids (3,4).
Application
Anti-CX3CR1 antibody produced in rabbit has been used in western blotting.
Biochem/physiol Actions
C-X3-C motif chemokine receptor 1 (CX3CR1) functions as a receptor for fractalkine. It is implicated in the progression of inflammatory and vascular disorders.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied in PBS with 0.02% sodium azide.
Other Notes
The action of this antibody can be blocked using blocking peptide SBP3500204.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
常规特殊物品
低风险生物材料
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Polymorphisms in the microglial marker molecule CX3CR1 affect the blood volume of the human brain
Sakai M, et al.
Psychiatry and Clinical Neurosciences, 72(6), 409-422 (2018)
Chris Rudyk et al.
Journal of neuroinflammation, 16(1), 120-120 (2019-06-09)
Leucine-rich repeat kinase 2 (LRRK2) is a common gene implicated in Parkinson's disease (PD) and is also thought to be fundamentally involved in numerous immune functions. Thus, we assessed the role of LRRK2 in the context of the effects of
Leucine-rich repeat kinase-2 (LRRK2) modulates paraquat-induced inflammatory sickness and stress phenotype
Rudyk C, et al.
Journal of Neuroinflammation, 16(1), 120-120 (2019)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| SBP3500204-0.05MG | 04061832168043 |
| SAB3500204-100UG | 04061832494876 |