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T0647

TAPS sodium salt

≥99% (titration)

Synonym(s):

3-[N,N-Bis(2-hydroxyethyl)amino]-2-hydroxypropanesulfonic acid sodium salt, TAPS NA, N-tris(Hydroxymethyl)methyl-3-aminopropanesulfonic acid sodium-potassium salt, [(2-Hydroxy-1,1-bis(hydroxymethyl)ethyl)amino]-1-propanesulfonic acid sodium-potassium salt

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About This Item

Empirical Formula (Hill Notation):
C7H16NNaO6S
CAS Number:
91000-53-2
Molecular Weight:
265.26
NACRES:
NA.25
PubChem Substance ID:
24899903
UNSPSC Code:
12161700
MDL number:
MFCD00069903
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Quality Level

200

assay

≥99% (titration)

form

crystalline powder

impurities

≤1% water content (Karl Fischer)

useful pH range

7.7-9.1

pKa (25 °C)

8.4

solubility

water: 0.33 g/mL, clear to slightly hazy, colorless

cation traces

Pb: ≤5 ppm

application(s)

diagnostic assay manufacturing

SMILES string

[Na+].OCC(CO)(CO)NCCCS([O-])(=O)=O

InChI

1S/C7H17NO6S.Na/c9-4-7(5-10,6-11)8-2-1-3-15(12,13)14;/h8-11H,1-6H2,(H,12,13,14);/q;+1/p-1

InChI key

FEGYIWVHCSRXCG-UHFFFAOYSA-M

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General description

N-Tris(hydroxymethyl)methyl-3-aminopropanesulfonic acid (TAPS) is a zwitterionic ionic buffer that is widely used in capillary electrophoresis. As one of the key biological buffers, it maintains the required pH of the medium and exhibits various properties such as high water soluble, highly inert, and stable nature and extremely low absorbance of ultraviolet-visible (UV-vis) light. TAPS buffer also aids in stabilizing lysozyme against thermal denaturation. It is widely used in biology and biochemistry.

Application

TAPS sodium salt has been used along with filtered natural sea water (FSW) to stain live or fixed embryos.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000508502
0000508502
0000487071
0000487071
0000431868

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The effects of biological buffers TRIS, TAPS, TES on the stability of lysozyme
Pannuru P, et al.
International Journal of Biological Macromolecules, 112, 720-727 (2018)
Buffer Standards for the Physiological pH of the Zwitterionic Compound, TAPS, From 5 to 55? C
Roy L N, et al.
Journal of Solution Chemistry, 35, 551-566 (2006)
Capillary electrophoretic study of interactions of metal ions with crown ethers, a sulfated beta-cyclodextrin, and zwitterionic buffers present as additives in the background electrolyte
Muzikar M, et al.
Electrophoresis, 23(12) , 1796-802 (2002)

Global Trade Item Number

SKUGTIN
T0647-100G04061837335631
T0647-500G04061832551937
T0647-25G04061832551920

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