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U4625

Uridine 5′-diphosphoglucose disodium salt hydrate from Saccharomyces cerevisiae

Name: Uridine 5&#8242;-diphosphoglucose disodium salt hydrate from <I>Saccharomyces cerevisiae</I>
Brand: SIGMA

≥98%, from Saccharomyces cerevisiae, powder

Synonym(s):

UDP-Glc hydrate, UDPG hydrate

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About This Item

Empirical Formula (Hill Notation):

C₁₅H₂₂N₂Na₂O₁₇P₂ · xH₂O

CAS Number:

28053-08-9

Molecular Weight:

610.27 (anhydrous basis)

UNSPSC Code:

41106305

PubChem Substance ID:

24900648

NACRES:

NA.51

MDL number:

MFCD20441966

Assay:

≥98%

Biological source:

Saccharomyces cerevisiae

Form:

powder

Solubility:

water: 50 mg/mL, clear, colorless

Storage temp.:

−20°C

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Product Name

Uridine 5′-diphosphoglucose disodium salt hydrate from Saccharomyces cerevisiae, ≥98%

Quality Level

300

biological source

Saccharomyces cerevisiae

assay

≥98%

form

powder

solubility

water: 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

O.[Na+].[Na+].OC[C@H]1O[C@H](OP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C15H24N2O17P2.2Na.H2O/c18-3-5-8(20)10(22)12(24)14(32-5)33-36(28,29)34-35(26,27)30-4-6-9(21)11(23)13(31-6)17-2-1-7(19)16-15(17)25;;;/h1-2,5-6,8-14,18,20-24H,3-4H2,(H,26,27)(H,28,29)(H,16,19,25);;;1H2/q;2*+1;/p-2/t5-,6-,8-,9-,10+,11-,12-,13-,14-;;;/m1.../s1

InChI key

SRHFBUUOPANXBG-WSIJJEQHSA-L

Related Categories

Biochemicals

Nucleosides and Nucleotides

General description

Uridine diphosphate glucose (UDP-glucose) is a glycogen precursor. The transfer of glucose from UDP-glucose to growing glycogen chain is catalyzed by the enzyme glycogen synthase. The enzyme uridine diphosphate galactose-4-epimerase catalyzes the formation of UDP-glucose from UDP-galactose.

Application

Uridine 5′-diphosphoglucose disodium salt hydrate from Saccharomyces cerevisiae has been used as a substrate

for the PpIRX10 enzyme activity from Arabidopsis thaliana
in radiometric assay of glycosyltransferases (GTs)
in uridine diphosphate glucose (UDP-Glc) 4-epimerase assay in Arabidopsis thaliana samples

Biochem/physiol Actions

Uridine diphosphate glucose (UDP-glucose) is an essential mediator of the cellular metabolic pathways. In yeast, the high levels of trehalose and glycogen favor increased levels of UDP-glucose.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

涉药品监管产品

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A quaternary mechanism enables the complex biological functions of octameric human UDP-glucose pyrophosphorylase, a key enzyme in cell metabolism

Fuhring J, et al.

Scientific Reports, 5, 9618-9618 (2015)

Hypoglycemia as a Pathological Result in Medical Praxis

Type 1 Diabetes Complications (2011)

Inhibitory effect of UDP-glucose on cAMP generation and insulin secretion.

Fariborz Parandeh et al.

The Journal of biological chemistry, 295(45), 15245-15252 (2020-08-29)

Type-2 diabetes (T2D) is a global disease caused by the inability of pancreatic β-cells to secrete adequate insulin. However, the molecular mechanisms underlying the failure of β-cells to respond to glucose in T2D remains unknown. Here, we investigated the relative

Unravelling evolutionary strategies of yeast for improving galactose utilization through integrated systems level analysis

Hong KK, et al.

Proceedings of the National Academy of Sciences of the USA, 108(29), 12179-12184 (2011)

Distinct properties of the five UDP-D-glucose/UDP-D-galactose 4-epimerase isoforms of Arabidopsis thaliana

Barber C, et al.

The Journal of Biological Chemistry, 281(25), 17276-17285 (2006)

View All Related Papers

Articles

Glycosyltransferases

Enzymatic glycosyltransferase specificity challenges the one enzyme-one linkage concept.

Glycosyltransferases: Tools for Synthesis and Modification of Glycans

Explore tools for glycosyltransferase synthesis and modification of glycans, such as glycosyltransferases and nucleotide sugar donors.

Global Trade Item Number

SKU	GTIN
U4625-100MG	04061837409608
U4625-500MG	04061837409646
U4625-25MG	04061837409639
U4625-1G	04061837409622
U4625-10MG	04061837409615
U4625-5G	04061833008164

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