Skip to Content
Merck
CN

A0152

4-Aminopyridine

≥98%

Synonym(s):

4-Pyridinamine, 4-Pyridylamine, 4AP, Fampridine

Sign In to View Organizational & Contract Pricing.

Select a Size

About This Item

Empirical Formula (Hill Notation):
C5H6N2
CAS Number:
504-24-5
Molecular Weight:
94.11
EC Number:
207-987-9
UNSPSC Code:
12352200
MDL number:
MFCD00006439
Beilstein/REAXYS Number:
105782

Key Documents

View All Documentation
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

InChI

1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)

InChI key

NUKYPUAOHBNCPY-UHFFFAOYSA-N

SMILES string

Nc1ccncc1

assay

≥98%

bp

273 °C (lit.)

mp

155-158 °C (lit.)

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

Non-selective K+ channel blocker; reverses saxitoxin- and tetrodotoxin-induced cardiorespiratory depression; increases stimulation-induced release of acetylcholine; induces depolarization of GABA neurons.

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1B

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

312.8 °F

flash_point_c

156 °C

Regulatory Information

新产品
This item has

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
090K3445
081K3482
072K3640
058H0363
057H3453

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

S A Doggrell et al.
Naunyn-Schmiedeberg's archives of pharmacology, 360(3), 317-323 (1999-10-30)
The effects of the outward rectifying potassium channel blocker, 4-aminopyridine, on contractile tone and on contractile responses to the spasmogens, 5-hydroxytryptamine and endothelin-1, were examined in pulmonary arteries (main and intralobar) and systemic vessels (aorta and mesenteric artery) from rats
G N Tseng
The Journal of pharmacology and experimental therapeutics, 290(2), 569-577 (1999-07-20)
4-Aminopyridine (4AP) binding to rKv1.4 occurs preferentially in the activated state, whereas binding to rKv4.2 occurs in the rested state. To explore structural basis for the different state dependencies of 4AP binding, regions of rKv1.4 that are likely to form
V Armand et al.
Brain research, 841(1-2), 62-69 (1999-11-05)
Patients with absence epilepsy frequently develop convulsions later in life. We were therefore interested whether tissue from rats with a genetic absence epilepsy is more prone to seizure generation than normal animals. We compared the epileptiform activities induced by 4-aminopyridine

Related Content

Product Information Sheet - A0152

Product Information Sheet

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service