A0207
(+)-Iron(II) L-ascorbate
≥90% (titration)
Synonym(s):
L-(+)-Ascorbic acid iron(II) salt, Ferrous ascorbate, Vitamin C iron(II) salt
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About This Item
Empirical Formula (Hill Notation):
C12H14FeO12
CAS Number:
Molecular Weight:
406.08
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.79
Assay
≥90% (titration)
form
crystalline
color
dark brown
SMILES string
[H][C@@]1(OC(=O)C(O)=C1O[Fe]OC2=C(O)C(=O)O[C@]2([H])[C@@H](O)CO)[C@@H](O)CO
InChI
1S/2C6H8O6.Fe/c2*7-1-2(8)5-3(9)4(10)6(11)12-5;/h2*2,5,7-10H,1H2;/q;;+2/p-2/t2*2-,5+;/m00./s1
InChI key
RFBYLSCVRUTUSB-ZZMNMWMASA-L
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Biochem/physiol Actions
(+)-Iron(II) L-ascorbate or ferrous ascorbate has high potential to absorb iron in vivo compared to ferrous sulfate. In children, it is used as an effective oral iron supplement to treat iron deficiency anemia.
Iron-ascorbate (ferrous-ascorbate) is used as a reagent in cell culture and other systems to evaluate various aspects of oxidative stress and anti-oxidation mechanisms.
Disclaimer
May darken in storage.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Treatment of iron deficiency anemia in children: a comparative study of ferrous ascorbate and colloidal iron
Yewale V N and Dewan B
Indian Journal of Pediatrics, 80(5), 385-390 (2013)
Complex stability of ferrous ascorbate in aqueous solution and its significance for iron absorption
Plug CM, et al.
Pharmaceutisch Weekblad. Scientific Edition, 6(6), 245-248 (1984)
Ingrid Wiswedel et al.
Free radical research, 44(2), 135-145 (2010-01-22)
The aim of this study was to investigate the effect of oxidative stress on mitochondrial phospholipids. In this context, this study investigated (i) the content of phosphatidylethanolamine (PE), phosphatidylcholine (PC) and cardiolipin (CL), (ii) the correlation of CL degradation with
Hanne Vorwerk et al.
Molecular microbiology, 93(6), 1224-1245 (2014-07-31)
The non-glycolytic food-borne pathogen Campylobacter jejuni successfully colonizes the intestine of various hosts in spite of its restricted metabolic properties. While several amino acids are known to be used by C. jejuni as energy sources, none of these have been
Bartosz Rózanowski et al.
Investigative ophthalmology & visual science, 49(7), 2838-2847 (2008-03-11)
To determine the effects of human retinal pigment epithelial (RPE) cell pigment granules on photosensitized and iron ion-mediated oxidation and the effect of the photodegradation of melanosomes on their antioxidant properties. RPE cells were isolated from human and bovine eyes;
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