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Merck
CN

A0207

(+)-Iron(II) L-ascorbate

≥90% (titration)

Synonym(s):

L-(+)-Ascorbic acid iron(II) salt, Ferrous ascorbate, Vitamin C iron(II) salt

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About This Item

Empirical Formula (Hill Notation):
C12H14FeO12
CAS Number:
24808-52-4
Molecular Weight:
406.08
NACRES:
NA.79
PubChem Substance ID:
24890411
UNSPSC Code:
12352200
EC Number:
246-469-7
MDL number:
MFCD00137682

Key Documents

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Product Name

(+)-Iron(II) L-ascorbate, ≥90% (titration)

InChI

1S/2C6H8O6.Fe/c2*7-1-2(8)5-3(9)4(10)6(11)12-5;/h2*2,5,7-10H,1H2;/q;;+2/p-2/t2*2-,5+;/m00./s1

InChI key

RFBYLSCVRUTUSB-ZZMNMWMASA-L

SMILES string

[H][C@@]1(OC(=O)C(O)=C1O[Fe]OC2=C(O)C(=O)O[C@]2([H])[C@@H](O)CO)[C@@H](O)CO

assay

≥90% (titration)

form

crystalline

color

dark brown

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Biochem/physiol Actions

(+)-Iron(II) L-ascorbate or ferrous ascorbate has high potential to absorb iron in vivo compared to ferrous sulfate. In children, it is used as an effective oral iron supplement to treat iron deficiency anemia.
Iron-ascorbate (ferrous-ascorbate) is used as a reagent in cell culture and other systems to evaluate various aspects of oxidative stress and anti-oxidation mechanisms.

Disclaimer

May darken in storage.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
057K2562
107H2525
071K2537
065H2659
020K2510

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Rame Taha et al.
PloS one, 5(7), e11817-e11817 (2010-08-03)
Although mitochondrial dysfunction and oxidative stress are central mechanisms in various pathological conditions, they have not been extensively studied in the gastrointestinal tract, which is known to be constantly exposed to luminal oxidants from ingested foods. Key among these is
Ingrid Wiswedel et al.
Free radical research, 44(2), 135-145 (2010-01-22)
The aim of this study was to investigate the effect of oxidative stress on mitochondrial phospholipids. In this context, this study investigated (i) the content of phosphatidylethanolamine (PE), phosphatidylcholine (PC) and cardiolipin (CL), (ii) the correlation of CL degradation with
V Marcil et al.
Clinical biochemistry, 44(10-11), 873-883 (2011-05-10)
The aims of the study were to test the susceptibility of THP-1 macrophages to develop oxidative stress and to deploy antioxidant defense mechanisms that insure the balance between the pro- and antioxidant molecules. Differentiated THP-1 were incubated in the presence
Dirk Hofreuter et al.
PloS one, 7(11), e50699-e50699 (2012-12-12)
Campylobacter jejuni is a major cause of food-borne disease in industrialized countries. Carbohydrate utilization by C. jejuni is severely restricted, and knowledge about which substrates fuel C. jejuni infection and growth is limited. Some amino acids have been shown to
Complex stability of ferrous ascorbate in aqueous solution and its significance for iron absorption
Plug CM, et al.
Pharmaceutisch Weekblad. Scientific Edition, 6(6), 245-248 (1984)
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