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Merck
CN

A0207

(+)-Iron(II) L-ascorbate

≥90% (titration)

Synonym(s):

L-(+)-Ascorbic acid iron(II) salt, Ferrous ascorbate, Vitamin C iron(II) salt

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About This Item

Empirical Formula (Hill Notation):
C12H14FeO12
CAS Number:
24808-52-4
Molecular Weight:
406.08
NACRES:
NA.79
PubChem Substance ID:
24890411
UNSPSC Code:
12352200
EC Number:
246-469-7
MDL number:
MFCD00137682

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InChI

1S/2C6H8O6.Fe/c2*7-1-2(8)5-3(9)4(10)6(11)12-5;/h2*2,5,7-10H,1H2;/q;;+2/p-2/t2*2-,5+;/m00./s1

InChI key

RFBYLSCVRUTUSB-ZZMNMWMASA-L

SMILES string

[H][C@@]1(OC(=O)C(O)=C1O[Fe]OC2=C(O)C(=O)O[C@]2([H])[C@@H](O)CO)[C@@H](O)CO

assay

≥90% (titration)

form

crystalline

color

dark brown

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Biochem/physiol Actions

(+)-Iron(II) L-ascorbate or ferrous ascorbate has high potential to absorb iron in vivo compared to ferrous sulfate. In children, it is used as an effective oral iron supplement to treat iron deficiency anemia.
Iron-ascorbate (ferrous-ascorbate) is used as a reagent in cell culture and other systems to evaluate various aspects of oxidative stress and anti-oxidation mechanisms.

Disclaimer

May darken in storage.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
057K2562
107H2525
071K2537
065H2659
020K2510

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Hanne Vorwerk et al.
Molecular microbiology, 93(6), 1224-1245 (2014-07-31)
The non-glycolytic food-borne pathogen Campylobacter jejuni successfully colonizes the intestine of various hosts in spite of its restricted metabolic properties. While several amino acids are known to be used by C. jejuni as energy sources, none of these have been
Bartosz Rózanowski et al.
Investigative ophthalmology & visual science, 49(7), 2838-2847 (2008-03-11)
To determine the effects of human retinal pigment epithelial (RPE) cell pigment granules on photosensitized and iron ion-mediated oxidation and the effect of the photodegradation of melanosomes on their antioxidant properties. RPE cells were isolated from human and bovine eyes;
Hanne Vorwerk et al.
Molecular microbiology, 98(5), 809-830 (2015-08-12)
Thermophilic Campylobacter species colonize the intestine of agricultural and domestic animals commensally but cause severe gastroenteritis in humans. In contrast to other enteropathogenic bacteria, Campylobacter has been considered to be non-glycolytic, a metabolic property originally used for their taxonomic classification.
Dirk Hofreuter et al.
PloS one, 7(11), e50699-e50699 (2012-12-12)
Campylobacter jejuni is a major cause of food-borne disease in industrialized countries. Carbohydrate utilization by C. jejuni is severely restricted, and knowledge about which substrates fuel C. jejuni infection and growth is limited. Some amino acids have been shown to
V Marcil et al.
Clinical biochemistry, 44(10-11), 873-883 (2011-05-10)
The aims of the study were to test the susceptibility of THP-1 macrophages to develop oxidative stress and to deploy antioxidant defense mechanisms that insure the balance between the pro- and antioxidant molecules. Differentiated THP-1 were incubated in the presence
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