A1229
Angiopoietin-3 from mouse
recombinant, expressed in NSO cells, ≥90% (SDS-PAGE), lyophilized powder
Synonym(s):
ANG-3
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About This Item
MDL number:
UNSPSC Code:
51111800
biological source
mouse
recombinant
expressed in NSO cells
Assay
≥90% (SDS-PAGE)
form
lyophilized powder
mol wt
apparent mol wt 85-90 kDa by SDS-PAGE (reducing)
calculated mol wt ~58 kDa
storage condition
avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Gene Information
mouse ... Angptl1(72713)
Physical form
Lyophilized from a 0.2 μm filtered solution in 50 mM Tris citrate and 0.5 M sodium chloride, pH 6.5, containing 1.25 mg bovine serum albumin.
Analysis Note
The biological activity is measured by its ability to bind immobilized Tie-2/Fc in ELISA.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Regulatory Information
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K Teichert-Kuliszewska et al.
Cardiovascular research, 49(3), 659-670 (2001-02-13)
The endothelial cell (EC) specific tyrosine kinase receptor, Tie2, interacts with at least two ligands, angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2). Ang1 stimulates Tie2 receptor autophosphorylation, while Ang2 has been reported to inhibit Ang1-induced Tie2 receptor autophosphorylation. We studied the effects
D M Valenzuela et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(5), 1904-1909 (1999-03-03)
The angiopoietins have recently joined the members of the vascular endothelial growth factor family as the only known growth factors largely specific for vascular endothelium. The angiopoietins include a naturally occurring agonist, angiopoietin-1, as well as a naturally occurring antagonist
Sameer S Udhane et al.
Scientific reports, 5, 10132-10132 (2015-05-15)
Androgens are essential for sexual development and reproduction. However, androgen regulation in health and disease is poorly understood. We showed that human adrenocortical H295R cells grown under starvation conditions acquire a hyperandrogenic steroid profile with changes in steroid metabolizing enzymes
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