A126
(±)-HA-966
Synonym(s):
(±)-3-Amino-1-hydroxy-2-pyrrolidone
Sign Into View Organizational & Contract Pricing
Select a Size
About This Item
Empirical Formula (Hill Notation):
C4H8N2O2
CAS Number:
Molecular Weight:
116.12
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
SMILES string
NC1CCN(O)C1=O
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Regulatory Information
新产品
This item has
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
It looks like we've run into a problem, but you can still download Certificates of Analysis from our Documents section.
If you need assistance, please contact Customer Support
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Bradford D Fischer et al.
The journal of pain : official journal of the American Pain Society, 6(7), 425-433 (2005-07-05)
Although N-methyl-D-aspartate (NMDA) receptor antagonists clearly attenuate the development of tolerance to the antinociceptive effects of opioids, it is not clear whether they also alter acute opioid-induced antinociception. The present study was designed to assess NMDA/opioid interactions in C57BL/6 mice
Leandro J Bertoglio et al.
Psychopharmacology, 170(4), 335-342 (2003-09-19)
Drugs enhancing the GABA(A) and/or reducing the NMDA/glycine-B receptor activity produce an anxiolytic effect. Regarding the former drugs (e.g. benzodiazepines), prior elevated plus-maze (EPM) test experience abolishes the trial 2 anxiolytic activity, a phenomenon referred to as "one-trial tolerance" (OTT).
Melissa Nunnink et al.
Pharmacology, biochemistry, and behavior, 87(3), 321-330 (2007-06-15)
Conditioned taste aversion (CTA) is a form of associative learning in which the pairing of a taste with a toxin causes an animal to avoid the taste. NMDA receptor mediated neurotransmission has been implicated in CTA, but the role of
Luigi Cervo et al.
Psychopharmacology, 173(1-2), 124-131 (2004-01-09)
(+)-HA-966, a partial agonist at the glycine/NMDA modulatory site, significantly reduced i.v. cocaine self-administration in a fixed-ratio (FR) schedule. Since this effect was observed studying only one dose of cocaine and considering the characteristic bell-shaped curve generated by cocaine in
Frédéric Adam et al.
Neuropharmacology, 54(3), 588-596 (2008-01-08)
Using the C-fibre reflex as a nociceptive response elicited by a wide range of stimulus intensities in the rat, we recently reported that a single treatment with (+)-HA966, a glycine site-specific NMDA receptor antagonist: (1) potentiates morphine antinociception; and (2)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service