Merck
CN
All Photos(3)

Documents

A2093

Sigma-Aldrich

Aspirin

meets USP testing specifications

Sign Into View Organizational & Contract Pricing
All Photos(3)
Synonym(s):
Acetylsalicylic acid, 2-Acetoxybenzoic acid, O-Acetylsalicylic acid, ASA, Aspirin
Linear Formula:
2-(CH3CO2)C6H4CO2H
CAS Number:
50-78-2
Molecular Weight:
180.16
Beilstein:
779271
EC Number:
200-064-1
MDL number:
MFCD00002430
PubChem Substance ID:
24890623
NACRES:
NA.21

Agency

USP/NF
meets USP testing specifications

Quality Level

200

form

powder or crystals

mp

134-136 °C (lit.)

application(s)

pharmaceutical (small molecule)

SMILES string

CC(=O)Oc1ccccc1C(O)=O

InChI

1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)

InChI key

BSYNRYMUTXBXSQ-UHFFFAOYSA-N

Gene Information

human ... ITGA2B(3674) , PTGS1(5742) , PTGS2(5743)

Looking for similar products? Visit Product Comparison Guide

General description

Aspirin (acetylsalicylic acid) is a nonsteroidal anti-inflammatory drug. It occurs as white crystalline powder and is derived from salicylic acid.

Application

Aspirin has been used:
  • as a stabilizer for blood during 13,14-dihydro-15-keto-prostaglandin F2α (PGFM) measurement
  • to evaluate cell viability of BV-2 microglial cell line
  • in morphogenesis assay

Biochem/physiol Actions

Aspirin is an analgesic and antipyretic agent used in the treatment of fever and pain as in arthritis. It is also associated with cardiovascular diseases.
Blocks the production of prostaglandins by inhibiting cyclooxygenase (prostaglandin H synthase), with greater selectivity toward the COX-1 isoform. The antithrombotic effect is due to the inhibition of COX-1 in platelets that blocks thromboxane production and platelet aggregation. Chemopreventive against colorectal and other solid tumors.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H302

Precautionary Statements

P264 - P270 - P301 + P312 - P501

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

482.0 °F

Flash Point(C)

250 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Acetylsalicylic acid enhances the anti-inflammatory effect of fluoxetine through inhibition of NF-kB, p38-MAPK and ERK1/2 activation in lipopolysaccharide-induced BV-2 microglia cells
Yang JM, et al.
Neuroscience, 275, 296-394 (2014)
The 100 Most Important Chemical Compounds: A Reference Guide (2011)
Concise Clinical Pharmacology (2007)
Relationship between endotoxin and prostaglandin (PGE2 and PGFM) concentrations and ovarian function in dairy cows with puerperal endometritis
Mateus L, et al.
Animal Reproduction Science (2003)
Henry's Clinical Diagnosis and Management by Laboratory Methods E-book (2011)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service