A212000
DMT-2′O-TBDMS-rA(tac) Phosphoramidite
Synonym(s):
DMT-2′O-TBDMS-rA(tac) amidite, N-[[4-(1,1-dimethylethyl)phenoxy]acetyl]-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-adenosine, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
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About This Item
InChI
1S/C58H76N7O9PSi/c1-39(2)65(40(3)4)75(71-34-18-33-59)73-51-48(35-70-58(42-19-16-15-17-20-42,43-23-27-45(67-11)28-24-43)44-25-29-46(68-12)30-26-44)72-55(52(51)74-76(13,14)57(8,9)10)64-38-62-50-53(60-37-61-54(50)64)63-49(66)36-69-47-31-21-41(22-32-47)56(5,6)7/h15-17,19-32,37-40,48,51-52,55H,18,34-36H2,1-14H3,(H,60,61,63,66)/t48-,51-,52-,55-,75?/m1/s1
SMILES string
COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4c(NC(=O)COc5ccc(cc5)C(C)(C)C)ncnc34)(c6ccccc6)c7ccc(OC)cc7
InChI key
FWMHZIXOXNRHDJ-MGFFOSEMSA-N
product line
Proligo Reagents
assay
≥98% (31P-NMR), ≥98.0% (reversed phase HPLC)
form
solid
technique(s)
oligo synthesis: suitable
λ
conforms (UV/VIS Identity)
nucleoside profile
base: adenosine
base protecting group: TAC
2' protecting group: TBDMS
5' protecting group: DMT
deprotection: standard
storage temp.
−20°C
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Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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