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Merck
CN

A21203-HH

DMT-2′O-TBDMS-rA(tac) Phosphoramidite

configured for ABI

Synonym(s):

DMT-2′O-TBDMS-rA(tac) amidite, N-[[4-(1,1-dimethylethyl)phenoxy]acetyl]-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-[(1,1-dimethylethyl)dimethylsilyl]-adenosine, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]

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About This Item

Empirical Formula (Hill Notation):
C58H76N7O9PSi
CAS Number:
Molecular Weight:
1074.32
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
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product line

Proligo Reagents

assay

≥98% (31P-NMR), ≥98.0% (reversed phase HPLC)

form

solid

packaging

pkg of 1 × 0.5 g (A212031-01), pkg of 1 × 1 g (A212061-01), pkg of 12 × 4 g (A212064-12)

technique(s)

oligo synthesis: suitable

λ

conforms (UV/VIS Identity)

compatibility

configured for ABI

nucleoside profile

base: adenosine
base protecting group: TAC
2' protecting group: TBDMS
5' protecting group: DMT
deprotection: fast

storage temp.

−20°C

SMILES string

COc1ccc(cc1)C(OC[C@H]2O[C@H]([C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)n3cnc4c(NC(=O)COc5ccc(cc5)C(C)(C)C)ncnc34)(c6ccccc6)c7ccc(OC)cc7

InChI

1S/C58H76N7O9PSi/c1-39(2)65(40(3)4)75(71-34-18-33-59)73-51-48(35-70-58(42-19-16-15-17-20-42,43-23-27-45(67-11)28-24-43)44-25-29-46(68-12)30-26-44)72-55(52(51)74-76(13,14)57(8,9)10)64-38-62-50-53(60-37-61-54(50)64)63-49(66)36-69-47-31-21-41(22-32-47)56(5,6)7/h15-17,19-32,37-40,48,51-52,55H,18,34-36H2,1-14H3,(H,60,61,63,66)/t48-,51-,52-,55-,75?/m1/s1

InChI key

FWMHZIXOXNRHDJ-MGFFOSEMSA-N



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Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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