N-(6-Aminohexyl)-2-naphthalenesulfonamide hydrochloride

Name: N-(6-Aminohexyl)-2-naphthalenesulfonamide hydrochloride
Brand: SIGMA

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UNSPSC Code:

12352200

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storage temp.

2-8°C

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Lot/Batch Number

067F5012

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N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation.

H Hidaka et al.

Proceedings of the National Academy of Sciences of the United States of America, 78(7), 4354-4357 (1981-07-01)

N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide (W-7) and its derivatives are putative calmodulin antagonists that bind to calmodulin and inhibit Ca2+/calmodulin-regulated enzyme activities. Autoradiographic studies using tritiated W-7 showed that this compound penetrates the cell membrane, is distributed mainly in the cytoplasm, and inhibits proliferation

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