A2477
Asn-Arg-Cys-Ser-Gln-Gly-Ser-Cys-Trp-Asn (Disulfide Bridge 3-8)
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About This Item
Empirical Formula (Hill Notation):
C44H65N17O16S2
Molecular Weight:
1152.22
MDL number:
UNSPSC Code:
12352200
Assay
≥90% (HPLC)
storage temp.
−20°C
SMILES string
N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CO)NC1=O)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CC(N)=O)C(O)=O
Biochem/physiol Actions
Substrate for the disulfide bond-forming enzymes protein disulfide-isomerase (PDI) and DsbA (a periplasmic protein thiol:disulfide oxidoreductase).
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L W Ruddock et al.
The Biochemical journal, 315 ( Pt 3), 1001-1005 (1996-05-01)
A decapeptide containing two cysteine residues at positions 3 and 8 has been designed for use in monitoring the disulphide bond-forming activity of thiol:disulphide oxidoreductases. The peptide contains a tryptophan residue adjacent to one of the cysteine residues and an
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