A2658
Antipyrine
Sigma Reference Standard
Synonym(s):
2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one, Phenazone
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About This Item
Empirical Formula (Hill Notation):
C11H12N2O
CAS Number:
Molecular Weight:
188.23
EC Number:
200-486-6
UNSPSC Code:
12352005
PubChem Substance ID:
Beilstein/REAXYS Number:
157775
MDL number:
packaging
vial of 250 mg
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
mp
109-111 °C (lit.)
format
neat
SMILES string
CN1N(C(=O)C=C1C)c2ccccc2
InChI
1S/C11H12N2O/c1-9-8-11(14)13(12(9)2)10-6-4-3-5-7-10/h3-8H,1-2H3
InChI key
VEQOALNAAJBPNY-UHFFFAOYSA-N
Gene Information
human ... PTGS1(5742)
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Packaging
Supplied in amber screw-cap vials
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 1
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Regulatory Information
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Gro Klitgaard Povlsen et al.
BMC neuroscience, 14, 34-34 (2013-03-19)
Upregulation of vasoconstrictor receptors in cerebral arteries, including endothelin B (ETB) and 5-hydroxytryptamine 1B (5-HT(1B)) receptors, has been suggested to contribute to delayed cerebral ischemia, a feared complication after subarachnoid hemorrhage (SAH). This receptor upregulation has been shown to be
Antipyrine as a model drug to study hepatic drug-metabolizing capacity.
H E Poulsen et al.
Journal of hepatology, 6(3), 374-382 (1988-06-01)
Factors influencing antipyrine elimination.
I H Stevenson
British journal of clinical pharmacology, 4(3), 261-265 (1977-06-01)