A3253
Ala-Pro hydrate
≥98% (TLC), suitable for ligand binding assays
Synonym(s):
L-Alanyl-L-proline hydrate
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About This Item
Empirical Formula (Hill Notation):
C8H14N2O3 · xH2O
CAS Number:
Molecular Weight:
186.21 (anhydrous basis)
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352202
EC Number:
236-795-8
MDL number:
Beilstein/REAXYS Number:
3546017
Product Name
Ala-Pro hydrate,
InChI
1S/C8H14N2O3.H2O/c1-5(9)7(11)10-4-2-3-6(10)8(12)13;/h5-6H,2-4,9H2,1H3,(H,12,13);1H2/t5-,6-;/m0./s1
InChI key
SSUWZOPYGFOQJA-GEMLJDPKSA-N
SMILES string
O.C[C@H](N)C(=O)N1CCC[C@H]1C(O)=O
assay
≥98% (TLC)
form
powder
technique(s)
ligand binding assay: suitable
color
white to off-white
storage temp.
−20°C
Quality Level
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Related Categories
Biochem/physiol Actions
Alanyl dipeptides such as ala-leu, ala-lys, ala-gly, ala-pro, ala-tyr and ala-phe may be used in physicochemical studies or to evaluate dipeptide separation technologies. Alanyl dipeptides may also be used for studying cell uptake mechanisms, dipeptide metabolism or cell growth supplementation benefits.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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H Ke et al.
Proceedings of the National Academy of Sciences of the United States of America, 90(8), 3324-3328 (1993-04-15)
Cyclophilin is a binding protein for the immunosuppressive drug cyclosporin A and is also an enzyme with peptidyl-prolyl cis-trans isomerase activity. The crystal structure of cyclophilin A complexed with the substrate Ala-Pro has been determined and refined to an R
S Capasso et al.
Peptides, 19(2), 389-391 (1998-03-11)
Diketopiperazine formation from the N-terminal residues of a peptide chain is accelerated by aprotic dipolar protophobic solvents and catalyzed in organic solvents by alkylammonium carboxylate salts. The t1/2 for the first-order reaction of H-Ala-Pro-NH2 x TFA falls from 20 d
J Butterworth et al.
Journal of inherited metabolic disease, 8(4), 193-197 (1985-01-01)
Two forms of prolidase can be separated for all the human cells and tissues examined by DEAE-cellulose column chromatography or batch methods. Serum had a very low prolidase activity eluting as a single peak prior to tissue peak I prolidase.
I Naasani et al.
Biochimica et biophysica acta, 1231(2), 163-168 (1995-09-12)
The transport characteristics of ceftibuten, a dianionic cephem antibiotic, in rat renal and intestinal brush-border membranes were compared. Ceftibuten transport was mediated by two transport systems in the renal brush-border membrane and by one transport system in the intestinal brush-border
Lijiang Yang et al.
The Journal of chemical physics, 130(12), 124111-124111 (2009-04-02)
Recently, we introduced an integrated tempering approach to enhance sampling in the energy and configuration space for large systems. In this paper, we show that this new method has a higher efficiency than bias potential and generalized ensemble methods, such
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