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A3609

AC-55541

Name: AC-55541
Brand: SIGMA

≥98% (HPLC), powder

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About This Item

Empirical Formula (Hill Notation):

C₂₅H₂₀BrN₅O₃

Molecular Weight:

518.36

NACRES:

NA.77

PubChem Substance ID:

329770838

UNSPSC Code:

51101500

MDL number:

MFCD00327460

Assay:

≥98% (HPLC)

Form:

powder

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Properties

assay

≥98% (HPLC)

form

powder

solubility

DMSO: >5 mg/mL

storage temp.

2-8°C

SMILES string

C\C(=N/NC(=O)C(NC(=O)c1ccccc1)C2=NNC(=O)c3ccccc23)c4cccc(Br)c4

InChI

1S/C25H20BrN5O3/c1-15(17-10-7-11-18(26)14-17)28-31-25(34)22(27-23(32)16-8-3-2-4-9-16)21-19-12-5-6-13-20(19)24(33)30-29-21/h2-14,22H,1H3,(H,27,32)(H,30,33)(H,31,34)/b28-15+

InChI key

UCUHFWIFSHROPY-RWPZCVJISA-N

Description

Storage Class

13 - Non Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Certificates of Analysis (COA)

Lot/Batch Number

021M4602V

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Lipopolysaccharide pretreatment increases protease-activated receptor-2 expression and monocyte chemoattractant protein-1 secretion in vascular endothelial cells.

Hung-Hsing Chao et al.

Journal of biomedical science, 24(1), 85-85 (2017-11-17)

This study investigated whether lipopolysaccharide (LPS) increase protease-activated receptor-2 (PAR-2) expression and enhance the association between PAR-2 expression and chemokine production in human vascular endothelial cells (ECs). The morphology of ECs was observed through microphotography in cultured human umbilical vein

Exosome-mediated uptake of mast cell tryptase into the nucleus of melanoma cells: a novel axis for regulating tumor cell proliferation and gene expression.

Fabio Rabelo Melo et al.

Cell death & disease, 10(9), 659-659 (2019-09-12)

It is well established that mast cell accumulation accompanies most malignancies. However, the knowledge of how mast cells functionally impact on tumors is still rudimentary. Here we addressed this issue and show that mast cells have anti-proliferative activity on melanoma

Global Trade Item Number

SKU	GTIN
A3609-25MG	04061832258065
A3609-5MG	04061833458327