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Merck
CN

A4326

Arylamine acetyltransferase from pigeon liver

lyophilized powder, ~0.5 units/mg protein

Synonym(s):

NAT

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About This Item

CAS Number:
EC Number:
UNSPSC Code:
12352204
MDL number:
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biological source

pigeon liver

form

lyophilized powder

specific activity

~0.5 units/mg protein

composition

Protein, ~10% biuret

shipped in

dry ice

storage temp.

−20°C

Physical form

Contains sucrose as a stabilizer.

Other Notes

One unit will acetylate 1.0 nanomole of p-nitroaniline per min at pH 8.0 at 25 °C.


Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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Edith Sim et al.
Advances in pharmacology (San Diego, Calif.), 63, 169-205 (2012-07-11)
Arylamine N-acetyltransferases (NATs) are defined as xenobiotic metabolizing enzymes, adding an acetyl group from acetyl coenzyme A (CoA) to arylamines and arylhydrazines. NATs are found in organisms from bacteria and fungi to vertebrates. Several isoenzymes, often polymorphic, may be present
Mariola Rychlik-Sych et al.
Przeglad lekarski, 69(3), 120-124 (2012-07-07)
The etiology of dermatological diseases is still unknown. Involvement of genetic and environmental factors in the pathogenesis of dermatological diseases has contributed to a number of studies whose aim is to elucidate the way in which xenobiotics exert effects on
Yu Cai et al.
PloS one, 7(10), e47769-e47769 (2012-10-20)
Three first-line antituberculosis drugs, isoniazid, rifampicin and pyrazinamide, may induce liver injury, especially isoniazid. This antituberculosis drug-induced liver injury (ATLI) ranges from a mild to severe form, and the associated mortality cases are not rare. In the past decade, many