A4887
Asparaginase from Escherichia coli
Grade V, buffered aqueous glycerol solution, ≥80 units/mg protein
Synonym(s):
L-Asparagine Amidohydrolase
type
Grade V
form
buffered aqueous glycerol solution
specific activity
≥80 units/mg protein
storage temp.
2-8°C
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Physical form
Solution in 50% glycerol, pH 6.5
Analysis Note
Protein determined by biuret.
Other Notes
One unit will liberate 1.0 μmole of ammonia from L-asparagine per min at pH 8.6 at 37 °C.
Regulatory Information
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Fatal invasive aspergillosis of the larynx.
Mark S Williams et al.
European journal of haematology, 90(4), 354-354 (2012-12-12)
Juan Qiao et al.
Electrophoresis, 34(3), 409-416 (2012-11-20)
L-Asparaginase (L-Asnase) can suppress the growth of malignant cells by rapid depletion of two essential amino acids, L-glutamine (L-Gln) and L-asparagine (L-Asn). To study the cytotoxic effect and the secondary complications of L-Asnase in the treatment of acute lymphoblastic leukemia
Jonathan Seah et al.
Onkologie, 35(10), 596-598 (2012-10-06)
L-Asparaginase (L-Asp) may induce hypertriglyceridemia; however, this has been mainly observed among pediatric patients. Treatment for L-Asp-induced hypertriglyceridemia is not standardized, ranging from fasting and diet restriction to the invasive plasmapheresis procedure. We describe a 53-year-old male patient who presented
Jan Styczynski et al.
Anticancer research, 32(12), 5495-5499 (2012-12-12)
The analysis of the prognostic impact of residual disease at day 15 of induction therapy, individual tumor response testing (ITRT) at diagnosis, initial factors and initial therapy response to the risk of relapse in children with precursor B-cell acute lymphoblastic
[Feasibility and safety of chemotherapy for acute lymphoblastic leukemia in adolescents and young adults: Interim analysis of JALSG ALL202-U].
Eisei Kondo
[Rinsho ketsueki] The Japanese journal of clinical hematology, 53(8), 747-752 (2012-09-15)
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