A5284
8-Azaguanine
Hybri-Max™, γ-irradiated, powder, BioXtra, suitable for hybridoma
Synonym(s):
8-AzaG, 2-Amino-6-hydroxy-8-azapurine, 2-Amino-6-oxy-8-azapurine, Guanazolo
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About This Item
Empirical Formula (Hill Notation):
C4H4N6O
CAS Number:
Molecular Weight:
152.11
EC Number:
205-148-1
UNSPSC Code:
12352207
PubChem Substance ID:
Beilstein/REAXYS Number:
171098
MDL number:
InChI
1S/C4H4N6O/c5-4-6-2-1(3(11)7-4)8-10-9-2/h(H4,5,6,7,8,9,10,11)
InChI key
LPXQRXLUHJKZIE-UHFFFAOYSA-N
SMILES string
NC1=Nc2[nH]nnc2C(=O)N1
grade
Hybri-Max™
sterility
γ-irradiated
product line
BioXtra
form
powder
technique(s)
cell culture | hybridoma: suitable
mp
>300 °C (lit.)
storage temp.
−20°C
Application
For use in hybridoma cell culture applications as a myeloma selection agent.
Preparation Note
Reconstitute contents of vial with 10 mL sterile cell culture medium. Stock solution is sufficient to prepare 500 mL medium.
Legal Information
Hybri-Max is a trademark of Sigma-Aldrich Co. LLC
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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July Fong et al.
Scientific reports, 8(1), 1155-1155 (2018-01-20)
The threat of antibiotic resistant bacteria has called for alternative antimicrobial strategies that would mitigate the increase of classical resistance mechanism. Many bacteria employ quorum sensing (QS) to govern the production of virulence factors and formation of drug-resistant biofilms. Targeting
F R Ridzlan et al.
Tropical biomedicine, 27(3), 632-638 (2011-03-15)
Leptospirosis is recognized as one of the important zoonotic diseases in the world including Malaysia. A total of 145 soil and water samples were collected from selected National Service Training Centres (NSTC) in Kelantan and Terengganu. The samples were inoculated
S Grenacher et al.
Experimental & applied acarology, 25(8), 641-660 (2002-08-13)
Ticks are ectoparasites of vertebrates and utilize a variety of infochemicals for host finding and acceptance as well as for intraspecific aggregation and mating responses. Individual male and female Ixodes ricinus. the vector of Lyme disease in Europe. readily arrest
Qiao-Ling Gong et al.
Journal of molecular modeling, 18(2), 493-500 (2011-05-05)
The interaction between 8-azaguanine (8-Azan) and bovine serum albumin (BSA) in Tris-HCl buffer solutions at pH 7.4 was investigated by means of fluorescence and ultraviolet-visible (UV-Vis) spectroscopy. At 298 K and 310 K, at a wavelength of excitation (λ (ex))
Erwan Atcheson et al.
NPJ vaccines, 5, 92-92 (2020-10-22)
Malaria remains one of the world's most urgent global health problems, with almost half a million deaths and hundreds of millions of clinical cases each year. Existing interventions by themselves will not be enough to tackle infection in high-transmission areas.
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