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Merck
CN

A6481

Sigma-Aldrich

Allene Oxide Synthase from Parthenium argentatum

recombinant, expressed in E. coli, 25,000-40,000 units/mg protein

Synonym(s):

AOS, Allene Oxide Synthase Parthenium argentatum

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About This Item

EC Number:
UNSPSC Code:
12352204
NACRES:
NA.54
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recombinant

expressed in E. coli

form

solution

specific activity

25,000-40,000 units/mg protein

packaging

vial of ~300 μg

shipped in

dry ice

storage temp.

−20°C

Application

Allene Oxide Synthase is a potent anti-oxidant enzyme used to remove lipid hydroperoxides in various biological samples. It may also be used to study stress induced gene expression in plants . Product A6481 is from Parthenium argentatumand is supplied as a solution in phosphate buffered saline.

Biochem/physiol Actions

Allene oxide synthase converts lipoxygenase derived fatty acid hydroperoxides to unstable allene epoxides. In plants, allene oxide is a precursor of jasmonic acid, which is important for growth regulation .
Potent anti-oxidant enzyme to remove lipid hydroperoxides in biological samples.

Physical form

Supplied as a solution in phosphate buffered sale pH 7.2

Other Notes

One unit will cause a change in A234nm of 1.0 per minute at pH 7.0 at 25 °C in a 13S-HPOD((13(S)-hydroperoxy-(9Z,11E)-octadecanoic Acid) reduction assay

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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W J Esselman et al.
Journal of lipid research, 15(2), 173-178 (1974-03-01)
Alfalfa seeds and seedlings contain an enzyme that catalyzes a reaction with the 13- and 9-hydroperoxides of linoleic acid to form 13-hydroxy-10-oxo-trans-octadecenoic acid and 9-hydroxy-12-oxo-trans-10-octadecenoic acid, respectively. When commercial lipoxygenase is used to generate the hydroperoxides, the above acids appear
S Sivasankar et al.
Plant physiology, 122(4), 1335-1342 (2000-04-12)
Allene oxide synthase (AOS; hydroperoxide dehydratase; EC 4.2.1.92) catalyzes the first step in the biosynthesis of jasmonic acid from lipoxygenase-derived hydroperoxides of free fatty acids. Using the AOS cDNA from tomato (Lycopersicon esculentum), in which the role of jasmonic acid
Z Pan et al.
The Journal of biological chemistry, 270(15), 8487-8494 (1995-04-14)
Guayule plants accumulate large quantities of rubber within parenchyma cells of their stembark tissues. This rubber is packed within discrete organelles called rubber particles composed primarily of a lipophilic, cis-polyisoprene core, small amounts of lipids, and several proteins, the most
M Hamberg
Biochemical and biophysical research communications, 156(1), 543-550 (1988-10-14)
Incubation of 13(S)-hydroperoxy-9(Z),11(E),15(Z)-octadecatrienoic acid with corn (Zea mays L.) hydroperoxide dehydrase led to the formation of an unstable allene oxide derivative, 12,13(S)-epoxy-9(Z),11,15(Z)-octadecatrienoic acid. Further conversion of the allene oxide yielded two major products, i.e. alpha-ketol 12-oxo-13-hydroxy-9(Z),15(Z)-octadecadienoic acid, and 12-oxo-10,15(Z)-phytodienoic acid
D J Siler et al.
The Journal of allergy and clinical immunology, 98(5 Pt 1), 895-902 (1996-11-01)
Natural rubber latex sensitization is caused by proteins from the latex of Hevea brasiliensis, the Brazilian rubber tree. Alternative non-cross-reactive latex rubber sources are needed for the manufacture of nonallergenic medical devices (e.g., catheters) that require elasticity, which is not

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