A6883
Atropine methyl bromide
≥99% (TLC), powder
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About This Item
Empirical Formula (Hill Notation):
C18H26NO3 · Br
CAS Number:
Molecular Weight:
384.31
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
220-700-1
MDL number:
assay
≥99% (TLC)
form
powder
color
white to off-white
solubility
H2O: 50 mg/mL
SMILES string
Br.C[N]1(C)[C@@H]2CC[C@H]1C[C@@H](C2)OC(=O)C(CO)c3ccccc3
InChI
1S/C18H26NO3.BrH/c1-19(2)14-8-9-15(19)11-16(10-14)22-18(21)17(12-20)13-6-4-3-5-7-13;/h3-7,14-17,20H,8-12H2,1-2H3;1H/t14-,15+,16?,17?;
InChI key
YBFLMRSYEWDJEJ-ZNHDNBJUSA-N
Gene Information
human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)
Biochem/physiol Actions
Competitive muscarinic acetylcholine receptor antagonist that does not cross the blood-brain barrier.
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M M Knuepfer et al.
The American journal of physiology, 276(1 Pt 2), R103-R112 (1999-01-14)
It has been suggested that toxicity to cocaine is related to the relative rate of cocaine metabolism by cholinesterases and to activation of cholinergic receptors either directly or by reflex mechanisms. We examined these possibilities by altering cholinesterase activity and
Timothy A Yap et al.
Molecular cancer therapeutics, 10(2), 360-371 (2010-12-31)
AKT is frequently deregulated in cancer, making it an attractive anticancer drug target. CCT128930 is a novel ATP-competitive AKT inhibitor discovered using fragment- and structure-based approaches. It is a potent, advanced lead pyrrolopyrimidine compound exhibiting selectivity for AKT over PKA
G J Kirouac et al.
The American journal of physiology, 273(6 Pt 2), H2549-H2557 (1998-01-22)
Experiments were done in alpha-chloralose-anesthetized, paralyzed, and artificially ventilated rats to investigate the effect of L-glutamate (Glu) stimulation of the substantia nigra (SN) and ventral tegmental area (VTA) on arterial pressure (AP) and heart rate (HR). Glu stimulation of the