A7708
β-N-Acetylhexosaminidase from Aspergillus oryzae
lyophilized powder, ≥10 units/mg protein (Lowry)
Synonym(s):
β-N-Acetyl-D-hexosaminide N-acetyl-hexosaminohydrolase
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About This Item
form
lyophilized powder
specific activity
≥10 units/mg protein (Lowry)
composition
Protein, ~10% Lowry
storage temp.
2-8°C
Application
Stable biotransformation catalyst, for the synthesis of oligosaccharides.
Biochem/physiol Actions
Active on N-acetyl-β-D-glucosaminides and N-acetyl-β-D-galactosaminides.
Physical form
Contains MES buffer salts and EDTA
Other Notes
One unit will hydrolyze 1.0 μmole of p-nitrophenyl N-acetyl-β-D-glucosaminide to p-nitrophenol and N-acetyl-D-glucosamine per min at pH 5.0 at 30 °C.
signalword
Danger
hcodes
pcodes
Hazard Classifications
Resp. Sens. 1
Storage Class
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Regulatory Information
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Singh, S., et al.
Chemical Communications (Cambridge, England), 993-993 (1996)
Singh, S., et al.
Journal of the Chemical Society. Chemical Communications, 2227-2227 (1994)
Federica Vernuccio et al.
Recenti progressi in medicina, 103(12), 559-563 (2012-12-22)
Cardiorenal syndrome is a pathophysiological heart and kidney disorder, in which acute or chronic dysfunction of one organ induces a damage in the other. It's a syndrome more and more often encountered in clinical practice and this implies the need
David J Vocadlo
Current opinion in chemical biology, 16(5-6), 488-497 (2012-11-14)
The addition of N-acetylglucosamine (GlcNAc) O-linked to serine and threonine residues of proteins is known as O-GlcNAc. This post-translational modification is found within multicellular eukaryotes on hundreds of nuclear and cytoplasmic proteins. O-GlcNAc transferase (OGT) installs O-GlcNAc onto target proteins
Tyler Mark Pierson et al.
Molecular genetics and metabolism, 108(1), 65-69 (2012-11-20)
A 12 year-old female presented with a seven-year history of progressive muscle weakness, atrophy, tremor and fasciculations. Cognition was normal. Rectal biopsy revealed intracellular storage material and biochemical testing indicated low hexosaminidase activity consistent with juvenile-onset G(M2)-gangliosidosis. Genetic evaluation revealed
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