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A7824

6-Aminocaproic acid

Name: 6-Aminocaproic acid
Brand: SIGMA

synthetic (organic), ≥99%, antifibrinolytic agent, powder

Synonym(s):

ε-Aminocaproic acid, 6-Aminohexanoic acid, EACA

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About This Item

Linear Formula:

H₂N(CH₂)₅CO₂H

CAS Number:

60-32-2

Molecular Weight:

131.17

NACRES:

NA.77

PubChem Substance ID:

24278238

UNSPSC Code:

12352202

EC Number:

200-469-3

MDL number:

MFCD00008238

Beilstein/REAXYS Number:

906872

Assay:

≥99%

Form:

powder

Grade:

biotech. grade

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Product Name

6-Aminocaproic acid, BioUltra, ≥99%

biological source

synthetic (organic)

Quality Level

300

grade

biotech. grade

product line

BioUltra

assay

≥99%

form

powder

technique(s)

cell culture | mammalian: suitable

impurities

≤0.005% Phosphorus (P), ≤0.1% Insoluble matter

ign. residue

≤0.1%

mp

207-209 °C (dec.) (lit.)

solubility

H₂O: 0.5 M, clear, colorless

anion traces

chloride (Cl^-): ≤0.05%, sulfate (SO₄^2-): ≤0.05%

cation traces

Al: ≤0.0005%, Ca: ≤0.005%, Cu: ≤0.0005%, Fe: ≤0.0005%, K: ≤0.005%, Mg: ≤0.001%, NH₄⁺: ≤0.05%, Na: ≤0.02%, Pb: ≤0.001%, Zn: ≤0.0005%

storage temp.

room temp

SMILES string

NCCCCCC(O)=O

InChI

1S/C6H13NO2/c7-5-3-1-2-4-6(8)9/h1-5,7H2,(H,8,9)

InChI key

SLXKOJJOQWFEFD-UHFFFAOYSA-N

Gene Information

human ... PLAT(5327), PLG(5340)
rat ... Ppm1a(24666)

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Related Categories

Bioactive Small Molecule Inhibitors

Bioactive Small Molecules

Biochemicals

High-Purity Biochemicals and Reagents

Acids for Laboratory, Analysis, and Regulated Applications

Biochem/physiol Actions

Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis.

Lysine analog. Promotes rapid dissociation of plasmin, thereby inhibiting the activation of plasminogen and subsequent fibrinolysis. Reported to inhibit plasminogen binding to activated platelets. An early report indicated that it inhibits the activation of the first component of the complement system. Binds and inactivates Carboxypeptidase B.

Storage Class

11 - Combustible Solids

wgk

WGK 2

flash_point_f

404.6 - 408.2 °F

flash_point_c

207 - 209 °C

ppe

dust mask type N95 (US), Eyeshields, Gloves

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BB0347, from the lyme disease spirochete Borrelia burgdorferi, is surface exposed and interacts with the CS1 heparin-binding domain of human fibronectin.

Robert A Gaultney et al.

PloS one, 8(9), e75643-e75643 (2013-10-03)

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Methods in cell biology, 122, 379-393 (2014-05-27)

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Mesoscopic hydrogel molding to control the 3D geometry of bioartificial muscle tissues.

Weining Bian et al.

Nature protocols, 4(10), 1522-1534 (2009-10-03)

This protocol describes a cell/hydrogel molding method for precise and reproducible biomimetic fabrication of three-dimensional (3D) muscle tissue architectures in vitro. Using a high aspect ratio soft lithography technique, we fabricate polydimethylsiloxane (PDMS) molds containing arrays of mesoscopic posts with

Tissue-Engineered Human Myobundle System as a Platform for Evaluation of Skeletal Muscle Injury Biomarkers.

Alastair Khodabukus et al.

Toxicological sciences : an official journal of the Society of Toxicology, 176(1), 124-136 (2020-04-16)

Traditional serum biomarkers used to assess skeletal muscle damage, such as activity of creatine kinase (CK), lack tissue specificity and sensitivity, hindering early detection of drug-induced myopathies. Recently, a novel four-factor skeletal muscle injury panel (MIP) of biomarkers consisting of

Streptococcus pneumoniae choline-binding protein E interaction with plasminogen/plasmin stimulates migration across the extracellular matrix.

Cécile Attali et al.

Infection and immunity, 76(2), 466-476 (2007-12-12)

The virulence mechanisms leading Streptococcus pneumoniae to convert from nasopharyngeal colonization to a tissue-invasive phenotype are still largely unknown. Proliferation of infection requires penetration of the extracellular matrix, which occurs by recruitment of host proteases to the bacterial cell surface.

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Global Trade Item Number

SKU	GTIN
A7824-100G	04061833386460
A7824-25G	04061833386484
A7824-1KG	04061833386477
A7824-500G	04061832938868

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