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Merck
CN

A7877

Sigma-Aldrich

L-Alanine benzyl ester hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C10H13NO2 · HCl
CAS Number:
Molecular Weight:
215.68
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.26
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Assay

≥98% (TLC)

form

powder

color

white to off-white

storage temp.

−20°C

SMILES string

Cl.CC(N)C(=O)OCc1ccccc1

InChI

1S/C10H13NO2.ClH/c1-8(11)10(12)13-7-9-5-3-2-4-6-9;/h2-6,8H,7,11H2,1H3;1H

InChI key

RLMHWGDKMJIEHH-UHFFFAOYSA-N

Application

L-Alanine benzyl ester (ALAB) may be used as an organic reagent and as a cationic charge inducer in microemulsions.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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Elena Peira et al.
International journal of pharmaceutics, 346(1-2), 119-123 (2007-07-10)
The study reports pig-skin permeation and skin accumulation of miconazole nitrate (MCZ) from positively charged microemulsions containing water, 1-decanol/1-dodecanol (2:1, w/w), lecithin and/or decyl polyglucoside at different weight ratios, propylene glycol, 1,2 hexanediol and a cationic charge-inducing agent (stearylamine (ST)
M S Jie et al.
Lipids, 35(10), 1135-1145 (2000-12-05)
Primary amines (ammonia, methyl, propyl, octyl, octadecyl, phenyl, benzyl, phenethyl) including methyl esters of amino acids (glycine, DL-alanine, L-valine, L-leucine, L-tyrosine, and L-methionine), and secondary amines (dimethyl, diethyl, dipropyl, diisopropyl, dioctyl, and diphenyl) attack regiospecifically the central carbon atom of
Tayyaba Syed et al.
Journal of enzyme inhibition and medicinal chemistry, 26(5), 668-680 (2011-01-22)
2-(1-[(4-Chloro/methylphenylsulfonylamino)alkyl]-5-thioxo-4,5-dihydro-1,3,4-oxadiazoles (4a-e) were synthesized, in four steps, via the sulfonyl derivatives of l-amino acids (l-alanine, l-methionine and l-phenylalanine) 1a-e, the esters 2a-e, the hydrazides 3a-e and finally the cyclization to 4a-e. Alkylation of 4a-e with 1.0 mole eq. of substituted
Jose Manuel Ageitos et al.
Biomacromolecules, 17(1), 314-323 (2015-12-02)
The chemoenzymatic polymerization of amino acid monomers by proteases involves a two-step reaction: the formation of a covalent acyl-intermediate complex between the protease and the carboxyl ester group of the monomer and the subsequent deacylation of the complex by aminolysis

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