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A8535

Amitriptyline hydrochloride

drug standard, 1.0 mg/mL in methanol

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About This Item

Empirical Formula (Hill Notation):
C20H23N · HCl
CAS Number:
549-18-8
Molecular Weight:
313.86
UNSPSC Code:
41116107
PubChem Substance ID:
329770962
EC Number:
200-659-6
MDL number:
MFCD00012537
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grade

drug standard

assay

≥98%

concentration

1.0 mg/mL in methanol

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

format

single component solution

storage temp.

2-8°C

SMILES string

Cl[H].CN(C)CC\C=C1\c2ccccc2CCc3ccccc13

InChI

1S/C20H23N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-12H,7,13-15H2,1-2H3;1H

InChI key

KFYRPLNVJVHZGT-UHFFFAOYSA-N

Gene Information

human ... SLC6A2(6530), SLC6A4(6532)

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

Tricyclic antidepressant; inhibits the norepinephrine and serotonin transporters with Kis of 100 nM and 14.7 nM, respectively; high in vitro affinity for α1-adrenoceptors, serotonin and muscarinic acetylcholine receptors.
Tricyclic antidepressant; norepinephrine and serotonin transporter inhibitor; high in vitro affinity for α1-adrenoceptors, serotonin and muscarinic acetylcholine receptors.

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Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Storage Class

3 - Flammable liquids

wgk

WGK 1

flash_point_f

51.8 °F - closed cup

flash_point_c

11 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves

Regulatory Information

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Certificates of Analysis (COA)

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