A8651
Ala-Ser-His-Leu-Gly-Leu-Ala-Arg
≥95% (HPLC)
Synonym(s):
Anaphylatoxin C3a fragment 70-77
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About This Item
Empirical Formula (Hill Notation):
C35H61N13O10
CAS Number:
Molecular Weight:
823.94
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
assay
≥95% (HPLC)
storage temp.
−20°C
SMILES string
CC(C)CC(NC(=O)C(Cc1cnc[nH]1)NC(=O)C(CO)NC(=O)C(C)N)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CCCNC(N)=N)C(O)=O
Storage Class
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Regulatory Information
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T E Hugli et al.
Proceedings of the National Academy of Sciences of the United States of America, 74(5), 1826-1830 (1977-05-01)
Two peptides identical to the COOH-terminal sequence of human C3a anaphylatoxin and two analogs were synthesized by the solid-phase method and tested for biological activity. The synthetic COOH-terminal octapeptide, C3a-(70-77) or Ala-Ser-His-Leu-Gly-Leu-Ala-Arg, caused contraction of guinea pig ileum and uterus
D G Payan et al.
The Journal of experimental medicine, 156(3), 756-765 (1982-09-01)
Human C3a and the synthetic octapeptide C3a (70-77), which retains the activities of an anaphylatoxin, inhibit in a concentration-dependent manner the generation of leukocyte inhibitory factor (LIF) activity by human mononuclear leukocytes and T lymphocytes cultured with the mitogens phytohemagglutinin