A8853
Anti-phospho-ATF-2 (pThr71) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
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About This Item
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
species reactivity
human, rodent
technique(s)
western blot: 0.35-1.0 μg/mL using NIH3T3 cells
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... ATF2(1386)
mouse ... Atf2(11909)
rat ... Atf2(81647)
General description
Activating transcription factor-2 (ATF2) belongs to the leucine zipper family. This transcription factor associates with CRE domains and activates CRE-dependent transcription.
Rabbit Anti-phospho-ATF-2 (pThr71) antibody detects human ATF-2. The antibody is also expected to react with mouse, rat, chicken and frog ATF2 as they share 100% homology with the human antigen.
Rabbit Anti-phospho-ATF-2 (pThr71) antibody detects human ATF-2. The antibody is also expected to react with mouse, rat, chicken and frog ATF2 as they share 100% homology with the human antigen.
Immunogen
synthetic phosphopeptide corresponding to the region of human ATF2 containing threonine 71.
Application
Rabbit Anti-phospho-ATF-2 (pThr71) antibody can be used for western blot assays at 0.35-1.0μg/ml using NIH3T3 cells.
Physical form
Solution in Dulbecco′s phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, with 1.0 mg/mL BSA (IgG and protease free) and 0.05% sodium azide.
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S Gupta et al.
Science (New York, N.Y.), 267(5196), 389-393 (1995-01-20)
Treatment of cells with pro-inflammatory cytokines or ultraviolet radiation causes activation of the c-Jun NH2-terminal protein kinase (JNK). Activating transcription factor-2 (ATF2) was found to be a target of the JNK signal transduction pathway. ATF2 was phosphorylated by JNK on
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