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Merck
CN

A9160

Sigma-Aldrich

Atriopeptin I rat

≥95% (HPLC)

Synonym(s):

Atrial Natriuretic Peptide Fragment 5-25

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About This Item

Empirical Formula (Hill Notation):
C83H135N29O30S2
CAS Number:
Molecular Weight:
2083.27
MDL number:
UNSPSC Code:
12352200
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Assay

≥95% (HPLC)

UniProt accession no.

storage temp.

−20°C

SMILES string

CC[C@H](C)[C@@H]1NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CSSC[C@H](NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](C)NC(=O)CNC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CO)[C@@H](C)CC

Gene Information

rat ... Nppa(24602)

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Biochem/physiol Actions

Weak agonist at the cGMP-coupled ANF receptor; cardiac atrial peptide which selectively relaxes intestinal but not vascular smooth muscle.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

涉药品监管产品
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Certificates of Analysis (COA)

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M G Currie et al.
Science (New York, N.Y.), 223(4631), 67-69 (1984-01-06)
Mammalian cardiac atria have several biologically active peptides that exert profound effects on sodium excretion, urine volume, and smooth muscle tone. In the present study two such peptides of low molecular weight were purified and separated from each other on

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